White matter integrity of the whole brain is disrupted in ¢rst-episode schizophrenia

	White matter integrity of the whole brain is disrupted in ¢rst-episode schizophrenia
	Hao YH 1; Liu ZN1; Tan LH 2; Kuang F 2; Xu L1,4 ; Yi YH 1; Zhang ZS 2; Jiang TZ3; Gong GL 3; Liu HL 1; zheningl@hotmail.com ; jiangtz@nlpr.ia.ac.cn
	2006
发表期刊	NEUROREPORT
卷号	17 期号:1 页码:23-26
合作性质	其它
摘要	Diffusion tensor imaging studies in schizophrenia have demonstrated lower diffusion anisotropy within white matter that provides information about brain white matter integrity. We have examined whether white matter is abnormal in first-episode schizophrenia by using diffusion tensor imaging. Twenty-one schizophrenic patients and healthy controls underwent diffusion tensor imaging scans that analyzed by using a rigorous voxel-based approach. We found that fractional anisotropy in white matter of the patients was lower than that in controls at the cerebral pecluncle, frontal regions, inferior temporal gyrus, medial parietal lobes, hippocampal gyrus, insula, right anterior cingulum bundle and right corona radiata. These results suggested that white matter integrity of the whole brain was disrupted in early illness onset of schizophrenia.
关键词	Diffusion Tensor Imaging First-episode Schizophrenia Fractional Anisotropy White Matter
收录类别	SCI
语种	英语
文献类型	期刊论文
条目标识符	http://ir.kiz.ac.cn/handle/152453/10589
专题	科研部门_学习记忆的分子神经机制（徐林）
通讯作者	zheningl@hotmail.com; jiangtz@nlpr.ia.ac.cn
作者单位	1.The Institute of Mental Health,Central South University,Changsha,Hunan, 2.Department of Radiology,Second Xiangya Hospital,CentralSouthUniversity,Changsha,Hunan 3.National Laboratory of Pattern Recognition,Institute of Automation,ChineseA cademy of Sciences,Beijing 4.Laboratory of Learning and Memory,Kunming Institute of Zoology, Chinese Academyof Sciences,Kunming,Y unnan,PRChina
推荐引用方式 GB/T 7714	Hao YH,Liu ZN*,Tan LH,et al. White matter integrity of the whole brain is disrupted in ¢rst-episode schizophrenia[J]. NEUROREPORT,2006,17(1):23-26.
APA	Hao YH.,Liu ZN*.,Tan LH.,Kuang F.,Xu L.,...&jiangtz@nlpr.ia.ac.cn.(2006).White matter integrity of the whole brain is disrupted in ¢rst-episode schizophrenia.NEUROREPORT,17(1),23-26.
MLA	Hao YH,et al."White matter integrity of the whole brain is disrupted in ¢rst-episode schizophrenia".NEUROREPORT 17.1(2006):23-26.

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