KIZ OpenIR  > 科研部门  > 进化与功能基因组学(施鹏)
Changes in the rumen microbiome and metabolites reveal the effect of host genetics on hybrid crosses
Li ZP1; Wright ADG3; Zhang ZG*4; Li GY*2; Si HZ1; Wang XX1; Qian WX*1; qianwenxizj@163.com; zhangzhigang@mail.kiz.ac.cn; tcslgy@126.com
2016
发表期刊ENVIRONMENTAL MICROBIOLOGY REPORTS
卷号8期号:6页码:1016-1023
摘要The rumen microbiota plays important roles in nutrient metabolism and absorption of the host. However, it is poorly understood how host genetic variation shapes the community structure of the rumen microbiota and its metabolic phenotype. Here, we used sika deer (Cervus nippon) and elk (Cervus elaphus) to produce the following two types of hybrid offspring: sika deer f x elk o (SEH) and elk f x sika deer o (ESH). Then, we examined the rumen microbiome and metabolites in the parents and their hybrid offspring. The rumen microbiota in the hybrids differed from that in their parents, suggesting a significant effect of host genetics on the rumen microbiome that may have resulted from vertical transmission. The rumen metabolites displayed patterns similar to the structure of the rumen microbiome, with changes in the amounts of volatile fatty acids and metabolites of amino acids. The alanine, arginine, proline and phenylalanine pathways were enriched in the rumen of hybrid animals. The enriched metabolites in the above pathways were positively correlated with the bacteria Prevotella spp., Acetitomaculum spp., Quinella spp., Succinivibrio spp. and Ruminobacter spp. These results suggest that host genetics has a major impact on the rumen microbiome and metabolites in hybrid animals.
资助者This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication.
收录类别SCI
语种英语
资助者This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication. ; This work was supported by the Natural Science Founda- tion of China (NSFC) (31501984). The funders had no role in the study design, data collection and interpretation or in the decisionto submitthework for publication.
文献类型期刊论文
条目标识符http://ir.kiz.ac.cn/handle/152453/10755
专题科研部门_进化与功能基因组学(施鹏)
遗传资源与进化国家重点实验室
通讯作者qianwenxizj@163.com; zhangzhigang@mail.kiz.ac.cn; tcslgy@126.com
作者单位1.Jilin Provincial Key Laboratory for Molecular Biology of Special Economic Animals, Institute of Special Animal and Plant Sciences, Chinese Academy of Agricultural Sciences, Changchun, Jilin, China
2.School of Animal and Comparative Biomedical Sciences, University of Arizona, Tucson, Arizona, USA.
3.College of Animal Science, Tarim University, Alar, Xinjiang, China
4.State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China
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Li ZP,Wright ADG,Zhang ZG*,et al. Changes in the rumen microbiome and metabolites reveal the effect of host genetics on hybrid crosses[J]. ENVIRONMENTAL MICROBIOLOGY REPORTS,2016,8(6):1016-1023.
APA Li ZP.,Wright ADG.,Zhang ZG*.,Li GY*.,Si HZ.,...&tcslgy@126.com.(2016).Changes in the rumen microbiome and metabolites reveal the effect of host genetics on hybrid crosses.ENVIRONMENTAL MICROBIOLOGY REPORTS,8(6),1016-1023.
MLA Li ZP,et al."Changes in the rumen microbiome and metabolites reveal the effect of host genetics on hybrid crosses".ENVIRONMENTAL MICROBIOLOGY REPORTS 8.6(2016):1016-1023.
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