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	Cathelicidin-BF, a Snake Cathelicidin-Derived Antimicrobial Peptide, Could Be an Excellent Therapeutic Agent for Acne Vulgaris
	Wang YP1,5; Zhang ZY1,5; Yang HL1,5; Li JX1; You DW1; Yu HN*2,3; Lai R*1; Chen LL4; Guang HJ2,3; Li Z2,3; joannyu@live.cn; rlai@mail.kiz.ac.cn
	2011
发表期刊	PLOS ONE
卷号	6期号:7页码:e22120
合作性质	其它
摘要	Cathelicidins are a family of antimicrobial peptides acting as multifunctional effector molecules in innate immunity. Cathelicidin-BF has been purified from the snake venoms of Bungarus fasciatus and it is the first identified cathelicidin antimicrobial peptide in reptiles. In this study, cathelicidin-BF was found exerting strong antibacterial activities against Propionibacterium acnes. Its minimal inhibitory concentration against two strains of P. acnes was 4.7 mu g/ml. Cathelicidin-BF also effectively killed other microorganisms including Staphylococcus epidermidis, which was possible pathogen for acne vulgaris. Cathelicidin-BF significantly inhibited pro-inflammatory factors secretion in human monocytic cells and P. acnes-induced O(2)(center dot-) production of human HaCaT keratinocyte cells. Observed by scanning electron microscopy, the surfaces of the treated pathogens underwent obvious morphological changes compared with the untreated controls, suggesting that this antimicrobial peptide exerts its action by disrupting membranes of microorganisms. The efficacy of cathelicidin-BF gel topical administering was evaluated in experimental mice skin colonization model. In vivo anti-inflammatory effects of cathelicidin-BF were confirmed by relieving P. acnes-induced mice ear swelling and granulomatous inflammation. The anti-inflammatory effects combined with potent antimicrobial activities and O(2)(center dot-) production inhibition activities of cathelicidin-BF indicate its potential as a novel therapeutic option for acne vulgaris.
资助者	This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800).
收录类别	SCI
语种	英语
资助者	This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800). ; This work was supported by Chinese National Natural Science Foundation (30830021, 30800185, 31025025) and the Ministry of Science and Technology (2010CB529800).
文献类型	期刊论文
条目标识符	http://ir.kiz.ac.cn/handle/152453/10819
专题	科研部门_天然药物功能蛋白质学科组（赖仞） 科研部门_动物模型与人类重大疾病机理重点实验室
通讯作者	joannyu@live.cn; rlai@mail.kiz.ac.cn
作者单位	1.Biotoxin Units of Key Laboratory of Animal Models and Human Disease Mechanisms, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China 2.College of Life Sciences, Hebei Normal University, Shijiazhuang, Hebei, China 3.School of Life Science and Biotechnology, Dalian University of Technology, Dalian, Liaoning, China 4.Clinical Laboratory, The First Affiliated Hospital of Kunming Medical College, Kunming, Yunnan, China 5.Graduate School of the Chinese Academy of Sciences, Beijing, China
推荐引用方式 GB/T 7714	Wang YP,Zhang ZY,Yang HL,et al. Cathelicidin-BF, a Snake Cathelicidin-Derived Antimicrobial Peptide, Could Be an Excellent Therapeutic Agent for Acne Vulgaris[J]. PLOS ONE,2011,6(7):e22120.
APA	Wang YP.,Zhang ZY.,Yang HL.,Li JX.,You DW.,...&rlai@mail.kiz.ac.cn.(2011).Cathelicidin-BF, a Snake Cathelicidin-Derived Antimicrobial Peptide, Could Be an Excellent Therapeutic Agent for Acne Vulgaris.PLOS ONE,6(7),e22120.
MLA	Wang YP,et al."Cathelicidin-BF, a Snake Cathelicidin-Derived Antimicrobial Peptide, Could Be an Excellent Therapeutic Agent for Acne Vulgaris".PLOS ONE 6.7(2011):e22120.

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