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	N-methyl-D-aspartate receptor-dependent long-term potentiation in CA1 region affects synaptic expression of glutamate receptor subunits and associated proteins in the whole hippocampus
	Zhong WX1; Dong ZF2,3; Luo JH*1; Tian M2,3; Cao J2,3; Lu X*2,3,4,5; lxu@vip.163.com; luojianhong@zjuem.zju.edu.cn
	2006
发表期刊	NEUROSCIENCE BULLETIN
卷号	141期号:3页码:1399-1413
摘要	Long term potentiation in hippocampus, evoked by high-frequency stimulation, is mediated by two major glutamate receptor subtypes, alpha-amino-3-hydroxyl-5-methyl-4-isoxazole propionate receptors and N-methyl-D-aspartate receptors. Receptor subunit composition and its interaction with cytoplasmic proteins constitute different pathways regulating synaptic plasticity. Here, we provide further evidence that N-methyl-D-aspartate receptor-mediated long term potentiation evoked at hippocampal CA1 region of rats induced by high-frequency stimulation of the Schaffer collateral-commissural pathway in vivo is not dependent on N-methyl-D-aspartate receptor subunit NR2B. Applying semi-quantitative immunoblotting, we found that in the whole tetanized hippocampus, synaptic expression of the N-methyl-D-aspartate and a-amino-3-hydroxyl-5-methyl-4-isoxazole propionate receptor subunits (NR1, NR2A, glutamate receptor 1) and their associated partners, e.g. synaptic associated protein 97, postsynaptic density protein 95, a subunit of Ca(2+)/calmodulin-dependent protein kinase 11, neuronal nitricoxide synthase, increased 180 min post-high-frequency stimulation. Moreover, phosphorylation of Ca(2+)/calmodulin-dependent protein kinase II at thr286 and glutamate receptor 1 at ser831 was increased 30 min post-high-frequency stimulation and blocked by N-methyl-D-aspartate receptor antagonists (AP-5 and MK-801). In sham group and controls, these changes were not observed. The expression of several other synaptic proteins (NR2B, glutamate receptors 2/3, N-ethylmaleimide sensitive factor) was not affected by long term potentiation induction. In hippocampal homogenates, the level of these proteins remained unchanged. These data indicate that N-methyl-D-aspartate receptor-dependent long term potentiation in CA1 region in vivo mainly affects the synaptic expression of glutamate receptor subunits and associated proteins in the whole hippocampus. The alteration of molecular aspects can play a role in regulating the long-lasting synaptic modification in hippocampal long term potentiation in vivo.
关键词	Ltp Glutamate Receptors Phosphorylation Camkii Alpha Synaptosome
资助者	This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L.
收录类别	SCI
语种	英语
资助者	This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L. ; This work was supported by grants from the National Science Foundation of China (30530250) and the Na- tional Basic Research Program (2006CB500800) to L.X. and J.H.L.
文献类型	期刊论文
条目标识符	http://ir.kiz.ac.cn/handle/152453/10885
专题	科研部门_学习记忆的分子神经机制（徐林） 科研部门_动物模型与人类重大疾病机理重点实验室
通讯作者	lxu@vip.163.com; luojianhong@zjuem.zju.edu.cn
作者单位	1.Department of Neurobiology, Zhejiang University School of Medicine, 353 Yanan Road, Hangzhou 310006, PR China 2.China Key Laboratory of Animal Models and Human Disease Mech- anisms and Laboratory of Learning and Memory, Kunming Institute of Zoology, The Chinese Academy of Sciences, Kunming 650223, Yun- nan, PR China 3.Graduate School of the Chinese Academy of Sciences, Beijing 100039, PR China 4.Institute of Neuroscience, Shanghai Institutes for Biological Sciences, the Chinese Academy of Sciences, Shanghai 200031, PR China 5.Mental Health Institute, the 2nd Hospital of Xiangya Medical College, Central South University, Changsha 410011, PR China
推荐引用方式 GB/T 7714	Zhong WX,Dong ZF,Luo JH*,et al. N-methyl-D-aspartate receptor-dependent long-term potentiation in CA1 region affects synaptic expression of glutamate receptor subunits and associated proteins in the whole hippocampus[J]. NEUROSCIENCE BULLETIN,2006,141(3):1399-1413.
APA	Zhong WX.,Dong ZF.,Luo JH*.,Tian M.,Cao J.,...&luojianhong@zjuem.zju.edu.cn.(2006).N-methyl-D-aspartate receptor-dependent long-term potentiation in CA1 region affects synaptic expression of glutamate receptor subunits and associated proteins in the whole hippocampus.NEUROSCIENCE BULLETIN,141(3),1399-1413.
MLA	Zhong WX,et al."N-methyl-D-aspartate receptor-dependent long-term potentiation in CA1 region affects synaptic expression of glutamate receptor subunits and associated proteins in the whole hippocampus".NEUROSCIENCE BULLETIN 141.3(2006):1399-1413.

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20061411399.pdf（918KB）	期刊论文	出版稿	开放获取	CC BY-NC-SA	请求全文

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