The roles of TNFAIP2 in cancers and infectious diseases

doi:10.1111/jcmm.13822

	The roles of TNFAIP2 in cancers and infectious diseases
	Lin Jia 1; Yundong Shi 1; Yi Wen 2; Wei Li 3,4; Jing Feng 5; Ceshi Chen 2
	2018
发表期刊	Journal of Cellular and Molecular Medicine
期号	~页码:1–8
摘要	TNFα‐induced protein 2 (TNFAIP2) is a primary response gene of TNFα. TNFAIP2 is highly expressed in immune cells and the urinary bladder. The expression of TNFAIP2 is regulated by multiple transcription factors and signalling pathways, including NF‐κB, KLF5 and retinoic acid. Physiologically, TNFAIP2 appears to be a multiple functional mediator not only for inflammation, angiogenesis and tunneling nanotube (TNT) formation but also as a regulator of cell proliferation and migration. The expression of TNFAIP2 is frequently abnormal in human cancers and in infec- tious diseases. Due to its significant functions in cell proliferation, angiogenesis, migration and invasion, TNFAIP2 could be a potential diagnostic biomarker and therapeutic target for cancer.
关键词	Angiogenesis Inflammation Migration Nanotube Formation Proliferation Tnfaip2
DOI	10.1111/jcmm.13822
语种	英语
引用统计	被引频次：12[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.kiz.ac.cn/handle/152453/12259
专题	科研部门_动物模型与人类重大疾病机理重点实验室
通讯作者	Ceshi Chen
作者单位	1.Department of Biology, Yuxi Normal University, Yuxi, China 2.Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China 3.Department of Urology of the First People's Hospital of Yunnan Province, Kunming, China 4.Medical College of Kunming University of Science and Technology, Kunming, China 5.Department of Laboratory Medicine & Central Laboratory, Southern Medical University Affiliated Fengxian Hospital, Shanghai, China
推荐引用方式 GB/T 7714	Lin Jia,Yundong Shi,Yi Wen,et al. The roles of TNFAIP2 in cancers and infectious diseases[J]. Journal of Cellular and Molecular Medicine,2018(~):1–8.
APA	Lin Jia,Yundong Shi,Yi Wen,Wei Li,Jing Feng,&Ceshi Chen.(2018).The roles of TNFAIP2 in cancers and infectious diseases.Journal of Cellular and Molecular Medicine(~),1–8.
MLA	Lin Jia,et al."The roles of TNFAIP2 in cancers and infectious diseases".Journal of Cellular and Molecular Medicine .~(2018):1–8.

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