| Wound dressing from polyvinyl alcohol/chitosan electrospun fiber membrane loaded with OH-CATH30 nanoparticles | |
| Zou, Pengfei; Lee, Wen-Hui; Gao, Zhiqin; Qin, Di; Wang, Yuxia; Liu, Jiao; Sun, Tongyi; Gao, Yuanyuan | |
| 2020 | |
| 发表期刊 | CARBOHYDRATE POLYMERS
 |
| ISSN | 0144-8617 |
| 卷号 | 232 |
| 摘要 | Novel nanomaterials have been developed for antimicrobial and wound healing applications. Here, we report the preparation of a polyvinyl alcohol/chitosan (PVA/CS) nanofiber with carboxymethyl chitosan nanoparticles (CMCS-OH30 NPs) encapsulating the antibacterial peptide OH-CATH30 (OH-30). The PVA/CS nanofibers containing OH-30 NPs (NP-30-NFs) obtained via electrospinning could achieve a secondary embedded OH-30. The effect of NP-30-NFs on the release of OH-30 was investigated through high-performance liquid chromatography. The antibacterial activities of NP-30-NFs against Escherichia coli and Staphylococcus aureus were studied by bacterial plate counting. NP-30-NFs containing different concentrations of NPs were applied to mouse skin wounds to determine their effectiveness in promoting wound healing. Results showed that NP-30-NFs exhibited antibacterial properties and promoted skin wound healing. |
| 收录类别 | sci |
| 语种 | 英语 |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kiz.ac.cn/handle/152453/12700 |
| 专题 | 科研部门_生物毒素与人类疾病（张云） |
| 推荐引用方式 GB/T 7714 | Zou, Pengfei,Lee, Wen-Hui,Gao, Zhiqin,et al. Wound dressing from polyvinyl alcohol/chitosan electrospun fiber membrane loaded with OH-CATH30 nanoparticles[J]. CARBOHYDRATE POLYMERS,2020,232. |
| APA | Zou, Pengfei.,Lee, Wen-Hui.,Gao, Zhiqin.,Qin, Di.,Wang, Yuxia.,...&Gao, Yuanyuan.(2020).Wound dressing from polyvinyl alcohol/chitosan electrospun fiber membrane loaded with OH-CATH30 nanoparticles.CARBOHYDRATE POLYMERS,232. |
| MLA | Zou, Pengfei,et al."Wound dressing from polyvinyl alcohol/chitosan electrospun fiber membrane loaded with OH-CATH30 nanoparticles".CARBOHYDRATE POLYMERS 232(2020). |
| 条目包含的文件 | ||||||
| 文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
| 2021110105.pdf（2565KB） | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | 请求全文 | |
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