Evolutionary History, Genomic Adaptation to Toxic Diet, and Extinction of the Carolina Parakeet

	Evolutionary History, Genomic Adaptation to Toxic Diet, and Extinction of the Carolina Parakeet
	Gelabert, Pere; Sandoval-Velasco, Marcela; Serres, Aitor; de Manuel, Marc; Renom, Pere; Margaryan, Ashot; Stiller, Josefin; de-Dios, Toni; Fang, Qi; Feng, Shaohong; Manosa, Santi; Pacheco, George; Ferrando-Bernal, Manuel; Shi, Guolin; Hao, Fei; Chen, Xianqing; Petersen, Bent; Olsen, Remi-Andre; Navarro, Arcadi; Deng, Yuan; Dalen, Love; Marques-Bonet, Tomas; Zhang, Guojie; Antunes, Agostinho; Gilbert, M. Thomas P.; Lalueza-Fox, Carles
	2020
发表期刊	CURRENT BIOLOGY
ISSN	0960-9822
卷号	30 期号:1 页码:108
摘要	As the only endemic neotropical parrot to have recently lived in the northern hemisphere, the Carolina parakeet (Conuropsis carolinensis) was an iconic North American bird. The last surviving specimen died in the Cincinnati Zoo in 1918 [1]. The cause of its extinction remains contentious: besides excessive mortality associated to habitat destruction and active hunting, their survival could have been negatively affected by its range having become increasingly patchy [2] or by the exposure to poultry pathogens [3, 4]. In addition, the Carolina parakeet showed a pre-dilection for cockleburs, an herbaceousplant that contains a powerful toxin, carboxyatractyloside, or CAT [5], which did not seem to affect them but made the birds notoriously toxic to most predators [3]. To explore the demographic history of this bird, we generated the complete genomic sequence of a preserved specimen held in a private collection in Espinelves (Girona, Spain), as well as of a close extant relative, Aratinga solstitialis. We identified two non-synonymous genetic changes in two highly conserved proteins known to interact with CAT that could underlie a specific dietary adaptation to this toxin. Our genomic analyses did not reveal evidence of a dramatic past demographic decline in the Carolina parakeet; also, its genome did not exhibit the long runs of homozygosity that are signals of recent inbreeding and are typically found in endangered species. As such, our results suggest its extinction was an abrupt process and thus likely solely attributable to human causes.
收录类别	sci
语种	英语
文献类型	期刊论文
条目标识符	http://ir.kiz.ac.cn/handle/152453/12733
专题	科研部门_遗传多样性基因组学研究组（张国捷）
推荐引用方式 GB/T 7714	Gelabert, Pere,Sandoval-Velasco, Marcela,Serres, Aitor,et al. Evolutionary History, Genomic Adaptation to Toxic Diet, and Extinction of the Carolina Parakeet[J]. CURRENT BIOLOGY,2020,30(1):108.
APA	Gelabert, Pere.,Sandoval-Velasco, Marcela.,Serres, Aitor.,de Manuel, Marc.,Renom, Pere.,...&Lalueza-Fox, Carles.(2020).Evolutionary History, Genomic Adaptation to Toxic Diet, and Extinction of the Carolina Parakeet.CURRENT BIOLOGY,30(1),108.
MLA	Gelabert, Pere,et al."Evolutionary History, Genomic Adaptation to Toxic Diet, and Extinction of the Carolina Parakeet".CURRENT BIOLOGY 30.1(2020):108.

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