The Genome of Shaw's Sea Snake (Hydrophis curtus) Reveals Secondary Adaptation to Its Marine Environment

	The Genome of Shaw's Sea Snake (Hydrophis curtus) Reveals Secondary Adaptation to Its Marine Environment
	Peng, Changjun; Ren, Jin-Long; Deng, Cao; Jiang, Dechun; Wang, Jichao; Qu, Jiangyong; Chang, Jiang; Yan, Chaochao; Jiang, Ke; Murphy, Robert W.; Wu, Dong-Dong; Li, Jia-Tang
	2020
发表期刊	MOLECULAR BIOLOGY AND EVOLUTION
ISSN	0737-4038
卷号	37 期号:6 页码:1744-1760
摘要	The transition of terrestrial snakes to marine life similar to 10 Ma is ideal for exploring adaptive evolution. Sea snakes possess phenotype specializations including laterally compressed bodies, paddle-shaped tails, valvular nostrils, cutaneous respiration, elongated lungs, and salt glands, yet, knowledge on the genetic underpinnings of the transition remains limited. Herein, we report the first genome of Shaw's sea snake (Hydrophis curtus) and use it to investigate sea snake secondary marine adaptation. A hybrid assembly strategy obtains a high-quality genome. Gene family analyses date a pulsed codinggene expansion to similar to 20 Ma, and these genes associate strongly with adaptations to marine environments. Analyses of selection pressure and convergent evolution discover the rapid evolution of protein-coding genes, and some convergent features. Additionally, 108 conserved noncoding elements appear to have evolved quickly, and these may underpin the phenotypic changes. Transposon elements may contribute to adaptive specializations by inserting into genomic regions around functionally related coding genes. The integration of genomic and transcriptomic analyses indicates independent origins and different components in sea snake and terrestrial snake venom; the venom gland of the sea snake harbors the highest PLA2 (17.23%) expression in selected elapids and these genes may organize tandemly in the genome. These analyses provide insights into the genetic mechanisms that underlay the secondary adaptation to marine and venom production of this sea snake.
收录类别	sci
语种	英语
文献类型	期刊论文
条目标识符	http://ir.kiz.ac.cn/handle/152453/12793
专题	科研部门_进化与发育转录组学（吴东东）
推荐引用方式 GB/T 7714	Peng, Changjun,Ren, Jin-Long,Deng, Cao,et al. The Genome of Shaw's Sea Snake (Hydrophis curtus) Reveals Secondary Adaptation to Its Marine Environment[J]. MOLECULAR BIOLOGY AND EVOLUTION,2020,37(6):1744-1760.
APA	Peng, Changjun.,Ren, Jin-Long.,Deng, Cao.,Jiang, Dechun.,Wang, Jichao.,...&Li, Jia-Tang.(2020).The Genome of Shaw's Sea Snake (Hydrophis curtus) Reveals Secondary Adaptation to Its Marine Environment.MOLECULAR BIOLOGY AND EVOLUTION,37(6),1744-1760.
MLA	Peng, Changjun,et al."The Genome of Shaw's Sea Snake (Hydrophis curtus) Reveals Secondary Adaptation to Its Marine Environment".MOLECULAR BIOLOGY AND EVOLUTION 37.6(2020):1744-1760.

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2021110301.pdf（2763KB）	期刊论文	出版稿	开放获取	CC BY-NC-SA	请求全文