Neo-functionalization of a Teosinte branched 1 homologue mediates adaptations of upland rice

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	Neo-functionalization of a Teosinte branched 1 homologue mediates adaptations of upland rice
	Lyu, Jun; Huang, Liyu; Zhang, Shilai; Zhang, Yesheng; He, Weiming; Zeng, Peng; Zeng, Yan; Huang, Guangfu; Zhang, Jing; Ning, Min; Bao, Yachong; Zhao, Shilei; Fu, Qi; Wade, Len J.; Chen, Hua; Wang, Wen; Hu, Fengyi
	2020
发表期刊	NATURE COMMUNICATIONS
卷号	11 期号:1
摘要	The rice orthologue of maize domestication gene Teosinte branched 1 (Tb1) affects tillering. But, unlike maize Tb1 gene, it was not selected during domestication. Here, we report that an OsTb1 duplicate gene (OsTb2) has been artificially selected during upland rice adaptation and that natural variation in OsTb2 is associated with tiller number. Interestingly, transgenic rice overexpressing this gene shows increased rather than decreased tillering, suggesting that OsTb2 gains a regulatory effect opposite to that of OsTb1 following duplication. Functional analyses suggest that the OsTb2 protein positively regulates tillering by interacting with the homologous OsTb1 protein and counteracts the inhibitory effect of OsTb1 on tillering. We further characterize two functional variations within OsTb2 that regulate protein function and gene expression, respectively. These results not only present an example of neo-functionalization that generates an opposite function following duplication but also suggest that the Tb1 homologue has been selected in upland rice.
收录类别	sci
语种	英语
文献类型	期刊论文
条目标识符	http://ir.kiz.ac.cn/handle/152453/12819
专题	基因起源组
推荐引用方式 GB/T 7714	Lyu, Jun,Huang, Liyu,Zhang, Shilai,et al. Neo-functionalization of a Teosinte branched 1 homologue mediates adaptations of upland rice[J]. NATURE COMMUNICATIONS,2020,11(1).
APA	Lyu, Jun.,Huang, Liyu.,Zhang, Shilai.,Zhang, Yesheng.,He, Weiming.,...&Hu, Fengyi.(2020).Neo-functionalization of a Teosinte branched 1 homologue mediates adaptations of upland rice.NATURE COMMUNICATIONS,11(1).
MLA	Lyu, Jun,et al."Neo-functionalization of a Teosinte branched 1 homologue mediates adaptations of upland rice".NATURE COMMUNICATIONS 11.1(2020).

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