| The Genetic Structure of Chinese Hui Ethnic Group Revealed by Complete Mitochondrial Genome Analyses Using Massively Parallel Sequencing | |
| Chen, Chong; Li, Yuchun; Tao, Ruiyang; Jin, Xiaoye; Guo, Yuxin; Cui, Wei; Chen, Anqi; Yang, Yue; Zhang, Xingru; Zhang, Jingyi; Li, Chengtao; Zhu, Bofeng | |
| 2020 | |
| 发表期刊 | GENES
 |
| 卷号 | 11期号:11 |
| 摘要 | Mitochondrial DNA (mtDNA), coupled with maternal inheritance and relatively high mutation rates, provides a pivotal way for us to investigate the formation histories of populations. The Hui minority with Islamic faith is one of the most widely distributed ethnic groups in China. However, the exploration of Hui's genetic architecture from the complete mitochondrial genome perspective has not been detected yet. Therefore, in this study, we employed the complete mitochondrial genomes of 98 healthy and unrelated individuals from Northwest China, as well as 99 previously published populations containing 7274 individuals from all over the world as reference data, to comprehensively dissect the matrilineal landscape of Hui group. Our results demonstrated that Hui group exhibited closer genetic relationships with Chinese Han populations from different regions, which was largely attributable to the widespread of haplogroups D4, D5, M7, B4, and F1 in these populations. The demographic expansion of Hui group might occur during the Late Pleistocene. Finally, we also found that Hui group might have gene exchanges with Uygur, Tibetan, and Tajik groups in different degrees and retain minor genetic imprint of European-specific lineages, therefore, hinting the existence of multi-ethnic integration events in shaping the genetic landscape of Chinese Hui group. |
| 收录类别 | sci |
| 语种 | 英语 |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kiz.ac.cn/handle/152453/12905 |
| 专题 | 科研部门_分子人类学（孔庆鹏） |
| 推荐引用方式 GB/T 7714 | Chen, Chong,Li, Yuchun,Tao, Ruiyang,et al. The Genetic Structure of Chinese Hui Ethnic Group Revealed by Complete Mitochondrial Genome Analyses Using Massively Parallel Sequencing[J]. GENES,2020,11(11). |
| APA | Chen, Chong.,Li, Yuchun.,Tao, Ruiyang.,Jin, Xiaoye.,Guo, Yuxin.,...&Zhu, Bofeng.(2020).The Genetic Structure of Chinese Hui Ethnic Group Revealed by Complete Mitochondrial Genome Analyses Using Massively Parallel Sequencing.GENES,11(11). |
| MLA | Chen, Chong,et al."The Genetic Structure of Chinese Hui Ethnic Group Revealed by Complete Mitochondrial Genome Analyses Using Massively Parallel Sequencing".GENES 11.11(2020). |
| 条目包含的文件 | ||||||
| 文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
| 2021110109.pdf（5855KB） | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | 请求全文 | |
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