Genomic and Phenotypic Analyses Reveal Mechanisms Underlying Homing Ability in Pigeon

	Genomic and Phenotypic Analyses Reveal Mechanisms Underlying Homing Ability in Pigeon
	Shao, Yong; Tian, Hang-Yu; Zhang, Jing-Jing; Kharrati-Koopaee, Hamed; Guo, Xing; Zhuang, Xiao-Lin; Li, Ming-Li; Nanaie, Hojat Asadollahpour; Tafti, Elahe Dehghani; Shojaei, Bahador; Namavar, Mohammad Reza; Sotoudeh, Narges; Ayoola, Adeola Oluwakemi; Li, Jia-Li; Liang, Bin; Esmailizadeh, Ali; Wang, Shu; Wu, Dong-Dong
	2020
发表期刊	MOLECULAR BIOLOGY AND EVOLUTION
ISSN	0737-4038
卷号	37 期号:1 页码:134-148
摘要	The homing pigeon was selectively bred from the domestic pigeon for a homing ability over long distances, a very fascinating but complex behavioral trait. Here, we generate a total of 95 whole genomes from diverse pigeon breeds. Comparing the genomes from the homing pigeon population with those from other breeds identifies candidate positively selected genes, including many genes involved in the central nervous system, particularly spatial learning and memory such as LRP8. Expression profiling reveals many neuronal genes displaying differential expression in the hippocampus, which is the key organ for memory and navigation and exhibits significantly larger size in the homing pigeon. In addition, we uncover a candidate gene GSR (encoding glutathione-disulfide reductase) experiencing positive selection in the homing pigeon. Expression profiling finds that GSR is highly expressed in the wattle and visual pigment cell layer, and displays increased expression levels in the homing pigeon. In vitro, a magnetic field stimulates increases in calcium ion concentration in cells expressing pigeon GSR. These findings support the importance of the hippocampus (functioning in spatial memory and navigation) for homing ability, and the potential involvement of GSR in pigeon magnetoreception.
收录类别	sci
语种	英语
文献类型	期刊论文
条目标识符	http://ir.kiz.ac.cn/handle/152453/12930
专题	科研部门_进化与发育转录组学（吴东东）
推荐引用方式 GB/T 7714	Shao, Yong,Tian, Hang-Yu,Zhang, Jing-Jing,et al. Genomic and Phenotypic Analyses Reveal Mechanisms Underlying Homing Ability in Pigeon[J]. MOLECULAR BIOLOGY AND EVOLUTION,2020,37(1):134-148.
APA	Shao, Yong.,Tian, Hang-Yu.,Zhang, Jing-Jing.,Kharrati-Koopaee, Hamed.,Guo, Xing.,...&Wu, Dong-Dong.(2020).Genomic and Phenotypic Analyses Reveal Mechanisms Underlying Homing Ability in Pigeon.MOLECULAR BIOLOGY AND EVOLUTION,37(1),134-148.
MLA	Shao, Yong,et al."Genomic and Phenotypic Analyses Reveal Mechanisms Underlying Homing Ability in Pigeon".MOLECULAR BIOLOGY AND EVOLUTION 37.1(2020):134-148.

条目包含的文件
文件名称/大小	文献类型	版本类型	开放类型	使用许可
2021110101.pdf（1436KB）	期刊论文	出版稿	开放获取	CC BY-NC-SA	请求全文