High infiltration of CD20(+)B lymphocytes in extranodal natural killer/T-cell lymphoma is associated with better prognosis

	High infiltration of CD20(+)B lymphocytes in extranodal natural killer/T-cell lymphoma is associated with better prognosis
	Chen, Min-Min; Zeng, Guo-Peng; Li, Jing; Fu, Jun-Hong; Long, Ya-Yi; Pan, Jie-Ying; Wei, Lin-Zhi; Guan, Jie-Ying; Lin, Ying-Xi; You, Hua; Si, Cheng; Li, Wen-Xing; Liang, Yi-Jun; Liu, Da-Hai; Liu, Fang; Liu, Fang
	2020
发表期刊	BRITISH JOURNAL OF HAEMATOLOGY
ISSN	0007-1048
卷号	191 期号:5 页码:E116-E120
摘要	Immune cells have an uncertain function during the progression of extranodal natural killer/T-cell lymphoma (ENKTL). The present study determined the distribution, phenotype, and clinical significance of B lymphocytes in ENKTL. Immunohistochemistry indicated high infiltration of CD20(+)B lymphocytes in the tumour tissues of 40% of the patients, and that a high infiltration correlated with better overall survival. Moreover, B lymphocytes had an active mature phenotypein situand suppressed the proliferation of ENKTL cellsin vitro. These results suggest that tumour infiltration of CD20(+)B lymphocytes may be a new prognostic indicator for patients with ENKTL.
收录类别	sci
语种	英语
文献类型	期刊论文
条目标识符	http://ir.kiz.ac.cn/handle/152453/12943
专题	科研部门_动物模型与人类重大疾病机理重点实验室
推荐引用方式 GB/T 7714	Chen, Min-Min,Zeng, Guo-Peng,Li, Jing,et al. High infiltration of CD20(+)B lymphocytes in extranodal natural killer/T-cell lymphoma is associated with better prognosis[J]. BRITISH JOURNAL OF HAEMATOLOGY,2020,191(5):E116-E120.
APA	Chen, Min-Min.,Zeng, Guo-Peng.,Li, Jing.,Fu, Jun-Hong.,Long, Ya-Yi.,...&Liu, Fang.(2020).High infiltration of CD20(+)B lymphocytes in extranodal natural killer/T-cell lymphoma is associated with better prognosis.BRITISH JOURNAL OF HAEMATOLOGY,191(5),E116-E120.
MLA	Chen, Min-Min,et al."High infiltration of CD20(+)B lymphocytes in extranodal natural killer/T-cell lymphoma is associated with better prognosis".BRITISH JOURNAL OF HAEMATOLOGY 191.5(2020):E116-E120.

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