The concordance between the evolutionary trend and the clinical manifestation of the two SARS-CoV-2 variants

	The concordance between the evolutionary trend and the clinical manifestation of the two SARS-CoV-2 variants
	Hu, B; Liu, R; Tang, XL; Pan, YC; Wang, M; Tong, YQ; Ye, GM; Shen, GG; Ying, RC; Fu, AS; Li, D; Zhao, WX; Peng, J; Guo, J; Men, D; Yao, XM; Wang, YR; Zhang, H; Feng, ZH; Yu, JP; Chen, LJ; Deng, ZX; Lu, XM; Zhang, YP; Li, YR; Liu, BD; Yu, LL; Li, Y; Lu, J; Liu, TG
	2021
发表期刊	NATIONAL SCIENCE REVIEW
ISSN	2095-5138
卷号	8 期号:8
摘要	Coronavirus disease 2019 (COVID-19), the disease caused by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has developed into a global pandemic that continues to pose an enormous threat to public health and the global economy. Since the first SARS-CoV-2 genome was released [1], thousands of genetic variants have been identified in SARS-CoV-2 strains isolated from worldwide patients. Some variants in the spike (S) protein have been reported to be associated with functional changes in viral transmissibility or viral loads, such as the D614G variant [2,3], the N501Y change, the P681H substitution and deletion of DeltaH69-DeltaV70 [4]. However, there is currently little direct evidence linking the genomic variants and clinical severity of COVID-19.
收录类别	sci
语种	英语
文献类型	期刊论文
条目标识符	http://ir.kiz.ac.cn/handle/152453/13151
专题	科研部门_适应性进化与进化医学（吕雪梅）昆明动物研究所
推荐引用方式 GB/T 7714	Hu, B,Liu, R,Tang, XL,et al. The concordance between the evolutionary trend and the clinical manifestation of the two SARS-CoV-2 variants[J]. NATIONAL SCIENCE REVIEW,2021,8(8).
APA	Hu, B.,Liu, R.,Tang, XL.,Pan, YC.,Wang, M.,...&Liu, TG.(2021).The concordance between the evolutionary trend and the clinical manifestation of the two SARS-CoV-2 variants.NATIONAL SCIENCE REVIEW,8(8).
MLA	Hu, B,et al."The concordance between the evolutionary trend and the clinical manifestation of the two SARS-CoV-2 variants".NATIONAL SCIENCE REVIEW 8.8(2021).

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