Diversity Scaling Analysis of Chinese Gut Microbiomes Across Ethnicities and Lifestyles

	Diversity Scaling Analysis of Chinese Gut Microbiomes Across Ethnicities and Lifestyles
	Xiao, WM; Gao, DP; Chen, HJ; Qiao, YT; Ma, ZS; Duan, LC
	2021
发表期刊	FRONTIERS IN MICROBIOLOGY
卷号	12
摘要	Diversity scaling (changes) of human gut microbiome is important because it measures the inter-individual heterogeneity of diversity and other important parameters of population-level diversity. Understanding the heterogeneity of microbial diversity can be used as a reference for the personalized medicine of microbiome-associated diseases. Similar to diversity per se, diversity scaling may also be influenced by host factors, especially lifestyles and ethnicities. Nevertheless, this important topic regarding Chinese populations has not been addressed, to our best knowledge. Here, we fill the gap by applying a recent extension to the classic species-area relationship (SAR), i.e., diversity-area relationship (DAR), to reanalyze a large dataset of Chinese gut microbiomes covering the seven biggest Chinese ethnic groups (covering > 95% Chinese) living rural and urban lifestyles. Four DAR profiles were constructed to investigate the diversity scaling, diversity overlap, potential maximal diversity, and the ratio of local to global diversity of Chinese gut microbiomes. We discovered the following: (i) The diversity scaling parameters (z) at various taxon levels are little affected by either ethnicity or lifestyles, as exhibited by less than 0.5% differences in pairwise comparisons. (ii) The maximal accrual diversity (potential diversity) exhibited difference in only about 5% of pairwise comparisons, and all of the differences occurred in ethnicity comparisons (i.e., lifestyles had no effects). (iii) Ethnicity seems to have stronger effects than lifestyles across all taxon levels, and this may reflect the reality that China has been experiencing rapid urbanization in the last few decades, while the ethnic-related genetic background may change relatively little during the same period.
收录类别	sci
语种	英语
文献类型	期刊论文
条目标识符	http://ir.kiz.ac.cn/handle/152453/13380
专题	科研部门_计算生物与医学生态学（马占山）
推荐引用方式 GB/T 7714	Xiao, WM,Gao, DP,Chen, HJ,et al. Diversity Scaling Analysis of Chinese Gut Microbiomes Across Ethnicities and Lifestyles[J]. FRONTIERS IN MICROBIOLOGY,2021,12.
APA	Xiao, WM,Gao, DP,Chen, HJ,Qiao, YT,Ma, ZS,&Duan, LC.(2021).Diversity Scaling Analysis of Chinese Gut Microbiomes Across Ethnicities and Lifestyles.FRONTIERS IN MICROBIOLOGY,12.
MLA	Xiao, WM,et al."Diversity Scaling Analysis of Chinese Gut Microbiomes Across Ethnicities and Lifestyles".FRONTIERS IN MICROBIOLOGY 12(2021).

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