Tracing the genetic footprints of vertebrate landing in non-teleost ray-finned fishes

	Tracing the genetic footprints of vertebrate landing in non-teleost ray-finned fishes
	Bi, XP; Wang, K; Yang, LD; Pan, HL; Jiang, HF; Wei, QW; Fang, MQ; Yu, H; Zhu, CL; Cai, YR; He, YM; Gan, XN; Zeng, HH; Yu, DQ; Zhu, YA; Jiang, HF; Qiu, Q; Yang, HM; Zhang, YE; Wang, W; Zhu, M; He, SP; Zhang, GJ
	2021
发表期刊	CELL
ISSN	0092-8674
卷号	184 期号:5 页码:1377-+
摘要	Rich fossil evidence suggests that many traits and functions related to terrestrial evolution were present long before the ancestor of lobe- and ray-finned fishes. Here, we present genome sequences of the bichir, paddlefish, bowfin, and alligator gar, covering all major early divergent lineages of ray-finned fishes. Our analyses show that these species exhibit many mosaic genomic features of lobe- and ray-finned fishes. In particular, many regulatory elements for limb development are present in these fishes, supporting the hypothesis that the relevant ancestral regulation networks emerged before the origin of tetrapods. Transcriptome analyses confirm the homology between the lung and swim bladder and reveal the presence of functional lung-related genes in early ray-finned fishes. Furthermore, we functionally validate the essential role of a jawed vertebrate highly conserved element for cardiovascular development. Our results imply the ancestors of jawed vertebrates already had the potential gene networks for cardio-respiratory systems supporting air breathing.
收录类别	sci
语种	英语
文献类型	期刊论文
条目标识符	http://ir.kiz.ac.cn/handle/152453/13455
专题	科研部门_遗传多样性基因组学研究组（张国捷）
推荐引用方式 GB/T 7714	Bi, XP,Wang, K,Yang, LD,et al. Tracing the genetic footprints of vertebrate landing in non-teleost ray-finned fishes[J]. CELL,2021,184(5):1377-+.
APA	Bi, XP.,Wang, K.,Yang, LD.,Pan, HL.,Jiang, HF.,...&Zhang, GJ.(2021).Tracing the genetic footprints of vertebrate landing in non-teleost ray-finned fishes.CELL,184(5),1377-+.
MLA	Bi, XP,et al."Tracing the genetic footprints of vertebrate landing in non-teleost ray-finned fishes".CELL 184.5(2021):1377-+.

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2023031557.pdf（8471KB）	期刊论文	出版稿	开放获取	CC BY-NC-SA	请求全文