Genetic basis of ruminant headgear and rapid antler regeneration

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	Genetic basis of ruminant headgear and rapid antler regeneration
	Wang, Y; Zhang, CZ; Wang, NN; Li, ZP; Heller, RAM; Liu, R; Zhao, Y; Han, JG; Pan, XY; Zheng, ZQ; Dai, XQ; Chen, CS; Dou, ML; Peng, SJ; Chen, XQ; Liu, J; Li, M; Wang, K; Liu, C; Lin, ZS; Chen, L; Hao, F; Zhu, WB; Song, CC; Zhao, C; Zheng, CL; Wang, JM; Hu, SW; Li, CY; Yang, H; Jiang, L; Li, GY; Liu, MJ; Sonstegard, TS; Zhang, GJ; Jiang, Y; Wang, W; Qiu, Q
	2019
发表期刊	SCIENCE
ISSN	0036-8075
卷号	364 期号:6446 页码:1153-+
摘要	Ruminants are the only extant mammalian group possessing bony (osseous) headgear. We obtained 221 transcriptomes from bovids and cervids and sequenced three genomes representing the only two pecoran lineages that convergently lack headgear. Comparative analyses reveal that bovid horns and cervid antlers share similar gene expression profiles and a common cellular basis developed from neural crest stem cells. The rapid regenerative properties of antler tissue involve exploitation of oncogenetic pathways, and at the same time some tumor suppressor genes are under strong selection in deer. These results provide insights into the evolutionary origin of ruminant headgear as well as mammalian organ regeneration and oncogenesis.
收录类别	sci
语种	英语
文献类型	期刊论文
条目标识符	http://ir.kiz.ac.cn/handle/152453/13572
专题	基因起源组
推荐引用方式 GB/T 7714	Wang, Y,Zhang, CZ,Wang, NN,et al. Genetic basis of ruminant headgear and rapid antler regeneration[J]. SCIENCE,2019,364(6446):1153-+.
APA	Wang, Y.,Zhang, CZ.,Wang, NN.,Li, ZP.,Heller, RAM.,...&Qiu, Q.(2019).Genetic basis of ruminant headgear and rapid antler regeneration.SCIENCE,364(6446),1153-+.
MLA	Wang, Y,et al."Genetic basis of ruminant headgear and rapid antler regeneration".SCIENCE 364.6446(2019):1153-+.

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2023031503.pdf（1214KB）	期刊论文	出版稿	开放获取	CC BY-NC-SA	请求全文