YB-1 as an Oncoprotein: Functions, Regulation, Post-Translational Modifications, and Targeted Therapy

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	YB-1 as an Oncoprotein: Functions, Regulation, Post-Translational Modifications, and Targeted Therapy
	Yin, QY; Zheng, M; Luo, QM; Jiang, DW; Zhang, HF; Chen, CS
	2022
发表期刊	CELLS
卷号	11 期号:7
摘要	Y box binding protein 1 (YB-1) is a protein with a highly conserved cold shock domain (CSD) that also belongs to the family of DNA- and RNA-binding proteins. YB-1 is present in both the nucleus and cytoplasm and plays versatile roles in gene transcription, RNA splicing, DNA damage repair, cell cycle progression, and immunity. Cumulative evidence suggests that YB-1 promotes the progression of multiple tumor types and serves as a potential tumor biomarker and therapeutic target. This review comprehensively summarizes the emerging functions, mechanisms, and regulation of YB-1 in cancers, and further discusses targeted strategies.
收录类别	sci
语种	英语
文献类型	期刊论文
条目标识符	http://ir.kiz.ac.cn/handle/152453/13685
专题	科研部门_肿瘤生物学（陈策实）
推荐引用方式 GB/T 7714	Yin, QY,Zheng, M,Luo, QM,et al. YB-1 as an Oncoprotein: Functions, Regulation, Post-Translational Modifications, and Targeted Therapy[J]. CELLS,2022,11(7).
APA	Yin, QY,Zheng, M,Luo, QM,Jiang, DW,Zhang, HF,&Chen, CS.(2022).YB-1 as an Oncoprotein: Functions, Regulation, Post-Translational Modifications, and Targeted Therapy.CELLS,11(7).
MLA	Yin, QY,et al."YB-1 as an Oncoprotein: Functions, Regulation, Post-Translational Modifications, and Targeted Therapy".CELLS 11.7(2022).

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2023032932.pdf（4575KB）	期刊论文	出版稿	开放获取	CC BY-NC-SA	请求全文