Advances in Biomarkers and Endogenous Regulation of Breast Cancer Stem Cells

KIZ OpenIR > 科研部门 > 肿瘤生物学（陈策实）

	Advances in Biomarkers and Endogenous Regulation of Breast Cancer Stem Cells
	Chen, WM; Zhang, L; Liu, SL; Chen, CS
	2022
发表期刊	CELLS
卷号	11 期号:19
摘要	Breast cancer is one of the most common cancers. Even if breast cancer patients initially respond to treatment, developed resistance can lead to a poor prognosis. Cancer stem cells (CSCs) are a group of undifferentiated cells with self-renewal and multipotent differentiation characteristics. Existing evidence has shown that CSCs are one of the determinants that contribute to the heterogeneity of primary tumors. The emergence of CSCs causes tumor recurrence, metastasis, and therapeutic resistance. Previous studies indicated that different stemness-associated surface markers can identify other breast cancer stem cell (BCSC) subpopulations. Deciphering the critical signaling networks that are involved in the induction and maintenance of stemness is essential to develop novel BCSC-targeting strategies. In this review, we reviewed the biomarkers of BCSCs, critical regulators of BCSCs, and the signaling networks that regulate the stemness of BCSCs.
收录类别	sci
语种	英语
文献类型	期刊论文
条目标识符	http://ir.kiz.ac.cn/handle/152453/13688
专题	科研部门_肿瘤生物学（陈策实）
推荐引用方式 GB/T 7714	Chen, WM,Zhang, L,Liu, SL,et al. Advances in Biomarkers and Endogenous Regulation of Breast Cancer Stem Cells[J]. CELLS,2022,11(19).
APA	Chen, WM,Zhang, L,Liu, SL,&Chen, CS.(2022).Advances in Biomarkers and Endogenous Regulation of Breast Cancer Stem Cells.CELLS,11(19).
MLA	Chen, WM,et al."Advances in Biomarkers and Endogenous Regulation of Breast Cancer Stem Cells".CELLS 11.19(2022).

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2023032937.pdf（645KB）	期刊论文	出版稿	开放获取	CC BY-NC-SA	请求全文