Complete mitogenomes document substantial genetic contribution from the Eurasian Steppe into northern Pakistani Indo-Iranian speakers

KIZ OpenIR > 科研部门 > 分子人类学（孔庆鹏）

	Complete mitogenomes document substantial genetic contribution from the Eurasian Steppe into northern Pakistani Indo-Iranian speakers
	Rahman, ZU; Tian, JY; Gao, ZL; Wang, HT; Xia, WX; Yang, BY; Yang, LQ; Li, YC; Kong, QP
	2021
发表期刊	EUROPEAN JOURNAL OF HUMAN GENETICS
ISSN	1018-4813
卷号	29 期号:6 页码:1008-1018
摘要	To elucidate whether Bronze Age population dispersals from the Eurasian Steppe to South Asia contributed to the gene pool of Indo-Iranian-speaking groups, we analyzed 19,568 mitochondrial DNA (mtDNA) sequences from northern Pakistani and surrounding populations, including 213 newly generated mitochondrial genomes (mitogenomes) from Iranian and Dardic groups, both speakers from the ancient Indo-Iranian branch in northern Pakistan. Our results showed that 23% of mtDNA lineages with west Eurasian origin arose in situ in northern Pakistan since similar to 5000 years ago (kya), a time depth very close to the documented Indo-European dispersals into South Asia during the Bronze Age. Together with ancient mitogenomes from western Eurasia since the Neolithic, we identified five haplogroups (similar to 8.4% of maternal gene pool) with roots in the Steppe region and subbranches arising (age similar to 5-2 kya old) in northern Pakistan as genetic legacies of Indo-Iranian speakers. Some of these haplogroups, such as W3a1b that have been found in the ancient samples from the late Bronze Age to the Iron Age period individuals of Swat Valley northern Pakistan, even have sub-lineages (age similar to 4 kya old) in the southern subcontinent, consistent with the southward spread of Indo-Iranian languages. By showing that substantial genetic components of Indo-Iranian speakers in northern Pakistan can be traced to Bronze Age in the Steppe region, our study suggests a demographic link with the spread of Indo-Iranian languages, and further highlights the corridor role of northern Pakistan in the southward dispersal of Indo-Iranian-speaking groups.
收录类别	sci
语种	英语
文献类型	期刊论文
条目标识符	http://ir.kiz.ac.cn/handle/152453/13725
专题	科研部门_分子人类学（孔庆鹏）
推荐引用方式 GB/T 7714	Rahman, ZU,Tian, JY,Gao, ZL,et al. Complete mitogenomes document substantial genetic contribution from the Eurasian Steppe into northern Pakistani Indo-Iranian speakers[J]. EUROPEAN JOURNAL OF HUMAN GENETICS,2021,29(6):1008-1018.
APA	Rahman, ZU.,Tian, JY.,Gao, ZL.,Wang, HT.,Xia, WX.,...&Kong, QP.(2021).Complete mitogenomes document substantial genetic contribution from the Eurasian Steppe into northern Pakistani Indo-Iranian speakers.EUROPEAN JOURNAL OF HUMAN GENETICS,29(6),1008-1018.
MLA	Rahman, ZU,et al."Complete mitogenomes document substantial genetic contribution from the Eurasian Steppe into northern Pakistani Indo-Iranian speakers".EUROPEAN JOURNAL OF HUMAN GENETICS 29.6(2021):1008-1018.

条目包含的文件
文件名称/大小	文献类型	版本类型	开放类型	使用许可
2023032921.pdf（1628KB）	期刊论文	出版稿	开放获取	CC BY-NC-SA	请求全文