Immunoprotection effects of chicken egg yolk immunoglobulins (IgY) against Aeromonas veronii infection in Sinocyclocheilus grahami

	Immunoprotection effects of chicken egg yolk immunoglobulins (IgY) against Aeromonas veronii infection in Sinocyclocheilus grahami
	Li, YK; Huang, BZ; Sun, SJ; Liu, NY; Li, YQ; Lan, MW; Wang, XA; Zhang, YW; Wu, AL; Yang, SY; Wu, JY; Zeng, XY; Pan, XF; Du, XG
	2023
发表期刊	AQUACULTURE
ISSN	0044-8486
卷号	563
摘要	Sinocyclocheilus grahami (S. grahami) has been artificially bred since it was domesticated in early 21st century. However, the large-scale breeding has exposed that S. grahami is susceptible to Aeromonas veronii (A. veronii). Herein, the specific immunoglobulin of yolk (IgY) against A. veronii was produced, which showed high specificity and sensitivity to bind with A. veronii. The stability scopes of temperature and pH were 20-60 degrees C and 4-7, respectively. The specific IgY significantly inhibited the growth of A. veronii by direct agglutination. Injection with the specific IgY protected S. grahami coping A. veronii infection by increasing ROS elimination speed and reducing the inflammatory damage, analyzed by activity of antioxidative enzymes (CAT, SOD and GSH-Px) and expression of TNF-alpha and IFN-gamma genes, respectively. Our study will contribute to develop a type of antibiotic substitute IgY which could be applied to elevate the culture benefit in S. grahami.
收录类别	SCI
语种	英语
文献类型	期刊论文
条目标识符	http://ir.kiz.ac.cn/handle/152453/14046
专题	科研部门_系统进化与生物地理学（杨君兴）
推荐引用方式 GB/T 7714	Li, YK,Huang, BZ,Sun, SJ,et al. Immunoprotection effects of chicken egg yolk immunoglobulins (IgY) against Aeromonas veronii infection in Sinocyclocheilus grahami[J]. AQUACULTURE,2023,563.
APA	Li, YK.,Huang, BZ.,Sun, SJ.,Liu, NY.,Li, YQ.,...&Du, XG.(2023).Immunoprotection effects of chicken egg yolk immunoglobulins (IgY) against Aeromonas veronii infection in Sinocyclocheilus grahami.AQUACULTURE,563.
MLA	Li, YK,et al."Immunoprotection effects of chicken egg yolk immunoglobulins (IgY) against Aeromonas veronii infection in Sinocyclocheilus grahami".AQUACULTURE 563(2023).

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