Chromosome-level genome and recombination map of the male buffalo

	Chromosome-level genome and recombination map of the male buffalo
	Wang, XB; Li, ZP; Feng, T; Luo, XE; Xue, LT; Mao, CH; Cui, KQ; Li, H; Huang, JP; Huang, KW; Rehman, SU; Shi, DS; Wu, DD; Ruan, J; Liu, QY
	2023
发表期刊	GIGASCIENCE
ISSN	2047-217X
卷号	12
摘要	Background: The swamp buffalo (Bubalus bubalis carabanesis) is an economically important livestock supplying milk, meat, leather, and draft power. Several female buffalo genomes have been available, but the lack of high-quality male genomes hinders studies on chromosome evolution, especially Y, as well as meiotic recombination. Results: Here, a chromosome-level genome with a contig N50 of 72.2 Mb and a fine-scale recombination map of male buffalo were reported. We found that transposable elements (TEs) and structural variants (SVs) may contribute to buffalo evolution by influencing adjacent gene expression. We further found that the pseudoautosomal region (PAR) of the Y chromosome is subject to stronger purification selection. The meiotic recombination map showed that there were 2 obvious recombination hotspots on chromosome 8, and the genes around them were mainly related to tooth development, which may have helped to enhance the adaption of buffalo to inferior feed. Among several genomic features, TE density has the strongest correlation with recombination rates. Moreover, the TE subfamily, SINE/tRNA, is likely to play a role in driving recombination into SVs. Conclusions: The male genome and sperm sequencing will facilitate the understanding of the buffalo genomic evolution and functional research.
收录类别	SCI
语种	英语
文献类型	期刊论文
条目标识符	http://ir.kiz.ac.cn/handle/152453/14064
专题	科研部门_进化与发育转录组学（吴东东）
推荐引用方式 GB/T 7714	Wang, XB,Li, ZP,Feng, T,et al. Chromosome-level genome and recombination map of the male buffalo[J]. GIGASCIENCE,2023,12.
APA	Wang, XB.,Li, ZP.,Feng, T.,Luo, XE.,Xue, LT.,...&Liu, QY.(2023).Chromosome-level genome and recombination map of the male buffalo.GIGASCIENCE,12.
MLA	Wang, XB,et al."Chromosome-level genome and recombination map of the male buffalo".GIGASCIENCE 12(2023).

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