Comparative genomics reveals the hybrid origin of a macaque group

	Comparative genomics reveals the hybrid origin of a macaque group
	Zhang, BL; Chen, W; Wang, ZF; Pang, W; Luo, MT; Wang, S; Shao, Y; He, WQ; Deng, Y; Zhou, L; Chen, JW; Yang, MM; Wu, YJ; Wang, L; Fernández-Bellon, H; Molloy, S; Meunler, H; Wanert, F; Kuderna, L; Marques-Bonet, T; Roos, C; Qi, XG; Li, M; Liu, ZJ; Schierup, MH; Cooper, DN; Liu, JQ; Zheng, YT; Zhang, GJ; Wu, DD
	2023
发表期刊	SCIENCE ADVANCES
ISSN	2375-2548
卷号	9 期号:22
摘要	Although species can arise through hybridization, compelling evidence for hybrid speciation has been reported only rarely in animals. Here, we present phylogenomic analyses on genomes from 12 macaque species and show that the fascicularis group originated from an ancient hybridization between the sinica and silenus groups similar to 3.45 to 3.56 million years ago. The X chromosomes and low-recombination regions exhibited equal contributions from each parental lineage, suggesting that they were less affected by subsequent backcrossing and hence could have played an important role in maintaining hybrid integrity. We identified many reproduction-associated genes that could have contributed to the development of the mixed sexual phenotypes characteristic of the fascicularis group. The phylogeny within the silenus group was also resolved, and functional experimentation confirmed that all extant Western silenus species are susceptible to HIV-1 infection. Our study provides novel insights into macaque evolution and reveals a hybrid speciation event that has occurred only very rarely in primates.
收录类别	SCI
语种	英语
文献类型	期刊论文
条目标识符	http://ir.kiz.ac.cn/handle/152453/14065
专题	科研部门_进化与发育转录组学（吴东东）
推荐引用方式 GB/T 7714	Zhang, BL,Chen, W,Wang, ZF,et al. Comparative genomics reveals the hybrid origin of a macaque group[J]. SCIENCE ADVANCES,2023,9(22).
APA	Zhang, BL.,Chen, W.,Wang, ZF.,Pang, W.,Luo, MT.,...&Wu, DD.(2023).Comparative genomics reveals the hybrid origin of a macaque group.SCIENCE ADVANCES,9(22).
MLA	Zhang, BL,et al."Comparative genomics reveals the hybrid origin of a macaque group".SCIENCE ADVANCES 9.22(2023).

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