Large-scale snake genome analyses provide insights into vertebrate development

	Large-scale snake genome analyses provide insights into vertebrate development
	Peng, CJ; Wu, DD; Ren, JL; Peng, ZL; Ma, ZF; Wu, W; Lv, YY; Wang, Z; Deng, C; Jiang, K; Parkinson, CL; Qi, Y; Zhang, ZY; Li, JT
	2023
发表期刊	CELL
ISSN	0092-8674
卷号	186 期号:14 页码:2959+
摘要	Snakes are a remarkable squamate lineage with unique morphological adaptations, especially those related to the evolution of vertebrate skeletons, organs, and sensory systems. To clarify the genetic under-pinnings of snake phenotypes, we assembled and analyzed 14 de novo genomes from 12 snake families. We also investigated the genetic basis of the morphological characteristics of snakes using functional ex-periments. We identified genes, regulatory elements, and structural variations that have potentially contrib-uted to the evolution of limb loss, an elongated body plan, asymmetrical lungs, sensory systems, and digestive adaptations in snakes. We identified some of the genes and regulatory elements that might have shaped the evolution of vision, the skeletal system and diet in blind snakes, and thermoreception in infrared-sensitive snakes. Our study provides insights into the evolution and development of snakes and vertebrates.
收录类别	SCI
语种	英语
文献类型	期刊论文
条目标识符	http://ir.kiz.ac.cn/handle/152453/14071
专题	科研部门_进化与发育转录组学（吴东东）
推荐引用方式 GB/T 7714	Peng, CJ,Wu, DD,Ren, JL,et al. Large-scale snake genome analyses provide insights into vertebrate development[J]. CELL,2023,186(14):2959+.
APA	Peng, CJ.,Wu, DD.,Ren, JL.,Peng, ZL.,Ma, ZF.,...&Li, JT.(2023).Large-scale snake genome analyses provide insights into vertebrate development.CELL,186(14),2959+.
MLA	Peng, CJ,et al."Large-scale snake genome analyses provide insights into vertebrate development".CELL 186.14(2023):2959+.

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