Whole transcriptome analysis reveals dysregulation of molecular networks in schizophrenia

	Whole transcriptome analysis reveals dysregulation of molecular networks in schizophrenia
	Yang, JF; Long, Q; Zhang, YQ; Liu, YL; Wu, J; Zhao, XL; You, X; Li, XY; Liu, JW; Teng, ZW; Zeng, Y; Luo, XJ
	2023
发表期刊	ASIAN JOURNAL OF PSYCHIATRY
ISSN	1876-2018
卷号	85
摘要	To characterize the regulatory relationships between different types of transcripts and the altered molecular networks in schizophrenia (SCZ), we performed a whole transcriptome study by quantifying mRNAs, long noncoding RNAs (lncRNAs), miRNAs, and circular RNAs (circRNAs) in the same individuals simultaneously. A total of 807 dysregulated genes showed differential expression in SCZ cases compared with controls. Network-based analysis revealed dysregulation of molecular networks in SCZ. Finally, integration of the transcriptome data with published data identified promising SCZ candidate genes. Our study reveals that dysregulated mo-lecular networks and regulatory relationships between different types of transcript may have a role in SCZ.
收录类别	SCI
语种	英语
文献类型	期刊论文
条目标识符	http://ir.kiz.ac.cn/handle/152453/14134
专题	科研部门_神经系统疾病（罗雄剑）
推荐引用方式 GB/T 7714	Yang, JF,Long, Q,Zhang, YQ,et al. Whole transcriptome analysis reveals dysregulation of molecular networks in schizophrenia[J]. ASIAN JOURNAL OF PSYCHIATRY,2023,85.
APA	Yang, JF.,Long, Q.,Zhang, YQ.,Liu, YL.,Wu, J.,...&Luo, XJ.(2023).Whole transcriptome analysis reveals dysregulation of molecular networks in schizophrenia.ASIAN JOURNAL OF PSYCHIATRY,85.
MLA	Yang, JF,et al."Whole transcriptome analysis reveals dysregulation of molecular networks in schizophrenia".ASIAN JOURNAL OF PSYCHIATRY 85(2023).

条目包含的文件
文件名称/大小	文献类型	版本类型	开放类型	使用许可
2024053125.pdf（7162KB）	期刊论文	出版稿	开放获取	CC BY-NC-SA	请求全文