| Spider-Venom Peptides: Structure, Bioactivity, Strategy, and Research Applications |
| Guo, RY; Guo, G; Wang, AL; Xu, GC; Lai, R; Jin, H
|
| 2024
|
| 发表期刊 | MOLECULES
 |
| ISSN | 1420-3049
|
| 卷号 | 29期号:1 |
| 摘要 | Spiders (Araneae), having thrived for over 300 million years, exhibit remarkable diversity, with 47,000 described species and an estimated 150,000 species in existence. Evolving with intricate venom, spiders are nature's skilled predators. While only a small fraction of spiders pose a threat to humans, their venoms contain complex compounds, holding promise as drug leads. Spider venoms primarily serve to immobilize prey, achieved through neurotoxins targeting ion channels. Peptides constitute a major part of these venoms, displaying diverse pharmacological activities, and making them appealing for drug development. Moreover, spider-venom peptides have emerged as valuable tools for exploring human disease mechanisms. This review focuses on the roles of spider-venom peptides in spider survival strategies and their dual significance as pharmaceutical research tools. By integrating recent discoveries, it provides a comprehensive overview of these peptides, their targets, bioactivities, and their relevance in spider survival and medical research. |
| 收录类别 | sci
|
| 语种 | 英语
|
| 文献类型 | 期刊论文
|
| 条目标识符 | http://ir.kiz.ac.cn/handle/152453/14218
|
| 专题 | 科研部门_天然药物功能蛋白质学科组（赖仞）
|
推荐引用方式
GB/T 7714 |
Guo, RY,Guo, G,Wang, AL,et al. Spider-Venom Peptides: Structure, Bioactivity, Strategy, and Research Applications[J]. MOLECULES,2024,29(1).
|
| APA |
Guo, RY,Guo, G,Wang, AL,Xu, GC,Lai, R,&Jin, H.(2024).Spider-Venom Peptides: Structure, Bioactivity, Strategy, and Research Applications.MOLECULES,29(1).
|
| MLA |
Guo, RY,et al."Spider-Venom Peptides: Structure, Bioactivity, Strategy, and Research Applications".MOLECULES 29.1(2024).
|
修改评论