NextDenovo: an efficient error correction and accurate assembly tool for noisy long reads

	NextDenovo: an efficient error correction and accurate assembly tool for noisy long reads
	Hu, J; Wang, Z; Sun, ZY; Hu, BX; Ayoola, AO; Liang, F; Li, JJ; Sandoval, JR; Cooper, DN; Ye, K; Ruan, J; Xiao, CL; Wang, DP; Wu, DD; Wang, S
	2024
发表期刊	GENOME BIOLOGY
ISSN	1474-760X
卷号	25 期号:1
摘要	Long-read sequencing data, particularly those derived from the Oxford Nanopore sequencing platform, tend to exhibit high error rates. Here, we present NextDenovo, an efficient error correction and assembly tool for noisy long reads, which achieves a high level of accuracy in genome assembly. We apply NextDenovo to assemble 35 diverse human genomes from around the world using Nanopore long-read data. These genomes allow us to identify the landscape of segmental duplication and gene copy number variation in modern human populations. The use of NextDenovo should pave the way for population-scale long-read assembly using Nanopore long-read data.
收录类别	sci
语种	英语
文献类型	期刊论文
条目标识符	http://ir.kiz.ac.cn/handle/152453/14232
专题	科研部门_进化与发育转录组学（吴东东）
推荐引用方式 GB/T 7714	Hu, J,Wang, Z,Sun, ZY,et al. NextDenovo: an efficient error correction and accurate assembly tool for noisy long reads[J]. GENOME BIOLOGY,2024,25(1).
APA	Hu, J.,Wang, Z.,Sun, ZY.,Hu, BX.,Ayoola, AO.,...&Wang, S.(2024).NextDenovo: an efficient error correction and accurate assembly tool for noisy long reads.GENOME BIOLOGY,25(1).
MLA	Hu, J,et al."NextDenovo: an efficient error correction and accurate assembly tool for noisy long reads".GENOME BIOLOGY 25.1(2024).

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