An atlas of regulatory elements in chicken: A resource for chicken genetics and genomics

	An atlas of regulatory elements in chicken: A resource for chicken genetics and genomics
	Pan, ZY; Wang, Y; Wang, MS; Wang, YZ; Zhu, XN; Gu, SW; Zhong, CH; An, LQ; Shan, MZ; Damas, J; Halstead, MM; Guan, DL; Trakooljul, N; Wimmers, K; Bi, Y; Wu, S; Delany, ME; Bai, XC; Cheng, HH; Sun, CJ; Yang, N; Hu, XX; Lewin, HA; Fang, LZ; Zhou, HJ
	2023
发表期刊	SCIENCE ADVANCES
ISSN	2375-2548
卷号	9 期号:18
摘要	A comprehensive characterization of regulatory elements in the chicken genome across tissues will have sub-stantial impacts on both fundamental and applied research. Here, we systematically identified and characterized regulatory elements in the chicken genome by integrating 377 genome-wide sequencing datasets from 23 adult tissues. In total, we annotated 1.57 million regulatory elements, representing 15 distinct chromatin states, and predicted about 1.2 million enhancer-gene pairs and 7662 super-enhancers. This functional annotation of the chicken genome should have wide utility on identifying regulatory elements accounting for gene regulation underlying domestication, selection, and complex trait regulation, which we explored. In short, this comprehen-sive atlas of regulatory elements provides the scientific community with a valuable resource for chicken genetics and genomics.
收录类别	SCI
语种	英语
文献类型	期刊论文
条目标识符	http://ir.kiz.ac.cn/handle/152453/14349
专题	科研部门_进化与生物多样性基因组学（王明山）
推荐引用方式 GB/T 7714	Pan, ZY,Wang, Y,Wang, MS,et al. An atlas of regulatory elements in chicken: A resource for chicken genetics and genomics[J]. SCIENCE ADVANCES,2023,9(18).
APA	Pan, ZY.,Wang, Y.,Wang, MS.,Wang, YZ.,Zhu, XN.,...&Zhou, HJ.(2023).An atlas of regulatory elements in chicken: A resource for chicken genetics and genomics.SCIENCE ADVANCES,9(18).
MLA	Pan, ZY,et al."An atlas of regulatory elements in chicken: A resource for chicken genetics and genomics".SCIENCE ADVANCES 9.18(2023).

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2024061450.pdf（2462KB）	期刊论文	出版稿	开放获取	CC BY-NC-SA	请求全文