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First Nonhuman Primate-Sized Magnetic Particle Imaging System Based on Digital-Scanned Focus Field
Wei, ZC; Liu, YJ; Liu, SJ; Yu, XM; Zhang, HR; Zhu, T; Zhang, B; Zhang, YL; Huang, HD; Fan, Y; Li, HL; Wang, JH; Tian, J; Hui, H
2024
发表期刊IEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT
ISSN0018-9456
卷号73
摘要Magnetic particle imaging (MPI) is a burgeoning imaging modality that facilitates the reconstruction of position and concentration of superparamagnetic iron oxide nanoparticles. Its potential in clinical applications is substantial, leading to an increasing demand for larger bore sizes in MPI systems. However, the challenge lies in maintaining high resolution, sensitivity, and real-time imaging advantages in larger systems. In this article, we present the design of a 3-D MPI system tailored for nonhuman primates (NHP-MPI) with a bore size of 190 mm. The application of a 3-D digital-scanned focus field is applied to obtain highly sensitive imaging, and the system operates cooling-free under low gradient conditions. In imaging experiments involving a macaque's brain, our system demonstrated good quantitative performance. The 3-D MPI image yielded satisfactory results for fusion with other structural imaging modalities.
收录类别sci
语种英语
文献类型期刊论文
条目标识符http://ir.kiz.ac.cn/handle/152453/14381
专题管理、支撑部门_灵长类设施
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GB/T 7714
Wei, ZC,Liu, YJ,Liu, SJ,et al. First Nonhuman Primate-Sized Magnetic Particle Imaging System Based on Digital-Scanned Focus Field[J]. IEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT,2024,73.
APA Wei, ZC.,Liu, YJ.,Liu, SJ.,Yu, XM.,Zhang, HR.,...&Hui, H.(2024).First Nonhuman Primate-Sized Magnetic Particle Imaging System Based on Digital-Scanned Focus Field.IEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT,73.
MLA Wei, ZC,et al."First Nonhuman Primate-Sized Magnetic Particle Imaging System Based on Digital-Scanned Focus Field".IEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT 73(2024).
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