Long non-coding RNAs with essential roles in neurodegenerative disorders

KIZ OpenIR

	Long non-coding RNAs with essential roles in neurodegenerative disorders
	Xiong, WD; Lu, L; Li, JL
	2024
发表期刊	NEURAL REGENERATION RESEARCH
ISSN	1673-5374
卷号	19 期号:6 页码:1212-1220
摘要	Recently, with the advent of high-resolution and high-throughput sequencing technologies, an increasing number of long non-coding RNAs (lncRNAs) have been found to be involved in the regulation of neuronal function in the central nervous system with specific spatiotemporal patterns, across different neurodegenerative diseases. However, the underlying mechanisms of lncRNAs during neurodegeneration remain poorly understood. This review provides an overview of the current knowledge of the biology of lncRNAs and focuses on introducing the latest identified roles, regulatory mechanisms, and research status of lncRNAs in Alzheimer's disease, Parkinson's disease, Huntington's disease, and amyotrophic lateral sclerosis. Finally, this review discusses the potential values of lncRNAs as diagnostic biomarkers and therapeutic targets for neurodegenerative diseases, hoping to provide broader implications for developing effective treatments.
收录类别	sci
语种	英语
文献类型	期刊论文
条目标识符	http://ir.kiz.ac.cn/handle/152453/14440
专题	昆明动物研究所
推荐引用方式 GB/T 7714	Xiong, WD,Lu, L,Li, JL. Long non-coding RNAs with essential roles in neurodegenerative disorders[J]. NEURAL REGENERATION RESEARCH,2024,19(6):1212-1220.
APA	Xiong, WD,Lu, L,&Li, JL.(2024).Long non-coding RNAs with essential roles in neurodegenerative disorders.NEURAL REGENERATION RESEARCH,19(6),1212-1220.
MLA	Xiong, WD,et al."Long non-coding RNAs with essential roles in neurodegenerative disorders".NEURAL REGENERATION RESEARCH 19.6(2024):1212-1220.

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2024073057.pdf（3022KB）	期刊论文	出版稿	开放获取	CC BY-NC-SA	请求全文