Mechanistic Research on the Crosstalk Between Macrophage Polarization and Energy Metabolic Reprogramming in Hepatocellular Carcinoma

	Mechanistic Research on the Crosstalk Between Macrophage Polarization and Energy Metabolic Reprogramming in Hepatocellular Carcinoma
	Zhu, R; Na, JT; Tan, XY; Chen, XY; Tian, XR; Luo, JJ; Chen, YB; Zhong, LP
	2026
发表期刊	J. HEPATOCELL. CARCINOMA
卷号	13
摘要	Liver cancer is ranked as the sixth most prevalent and the third deadliest cancer worldwide. Macrophages play a crucial role in cancer resistance mechanisms, and the regulation of their polarization state can alter their anti-tumor activity. Additionally, alterations in liver cancer pathways can shift the polarization of macrophages. Inflammatory agents and medications have the potential to alter macrophage polarization, favoring M1 differentiation and enhancing their anti-tumor activity. This review explores metabolic alterations in liver cancer, macrophage polarization processes, and their interconnections in hepatic oncogenesis. It further elaborates on the prospects and challenges of investigating targeted macrophage metabolism for liver cancer treatment. Modulating macrophage metabolic pathways represents a promising therapeutic approach for hepatic carcinoma.
收录类别	SCIE
语种	英语
文献类型	期刊论文
条目标识符	http://ir.kiz.ac.cn/handle/152453/14908
专题	科研部门_肿瘤信号转导（陈勇彬）
推荐引用方式 GB/T 7714	Zhu, R,Na, JT,Tan, XY,et al. Mechanistic Research on the Crosstalk Between Macrophage Polarization and Energy Metabolic Reprogramming in Hepatocellular Carcinoma[J]. J. HEPATOCELL. CARCINOMA,2026,13.
APA	Zhu, R.,Na, JT.,Tan, XY.,Chen, XY.,Tian, XR.,...&Zhong, LP.(2026).Mechanistic Research on the Crosstalk Between Macrophage Polarization and Energy Metabolic Reprogramming in Hepatocellular Carcinoma.J. HEPATOCELL. CARCINOMA,13.
MLA	Zhu, R,et al."Mechanistic Research on the Crosstalk Between Macrophage Polarization and Energy Metabolic Reprogramming in Hepatocellular Carcinoma".J. HEPATOCELL. CARCINOMA 13(2026).

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2026070104.pdf（4375KB）	期刊论文	出版稿	开放获取	CC BY-NC-SA	请求全文