Conserved chromosome segments in Hylobates hoolock revealed by human and H-leucogenys paint probes

KIZ OpenIR > 遗传资源与进化国家重点实验室 > 保护遗传学(细胞库)

	Conserved chromosome segments in Hylobates hoolock revealed by human and H-leucogenys paint probes
	Nie W 1; Rens W 2; Wang J 1; Yang F*2; fy@mole.bio.cam.ac.uk
	2001
发表期刊	CYTOGENETICS AND CELL GENETICS
ISSN	0301-0171
卷号	92 期号:3-4 页码:248-253
摘要	A complete comparative chromosome map of the white-browed gibbon (Hylobates hoolock, 2n = 38), white-cheeked gibbon (Hylobates leucogenys, 2n = 52), and human has been established by hybridising H. leucogenys chromosome-specific paints and human 24-colour paints onto H. hoolock metaphase chromosomes. In the 18 H. hoolock autosomes, we identified 62 conserved segments that showed DNA homology to regions of the 25 H. leucogenys autosomes, Numerous interchromosomal rearrangements differentiate the karyotypes of H. leucogenys and H. hoolock. Only H. hoolock chromosome 10 showed homology to one entire autosome of H. leucogenys. The hybridisation of human 24-colour paints not only confirmed most of the chromosome correspondences between human and H. hoolock established previously but also helped to correct five erroneous assignments and revealed three new segments. Our results demonstrate that the karyotypes of the extant gibbons have arisen mainly through extensive translocation events and that the karyotype of H. hoolock more closely resembles the ancestral karyotype of Hylobates, rather than the karyotype of H. leucogenys.
资助者	Supported in part by the Bai Ren Ji Hua fund of the Chinese Academy of Sciences ; Supported in part by the Bai Ren Ji Hua fund of the Chinese Academy of Sciences ; Supported in part by the Bai Ren Ji Hua fund of the Chinese Academy of Sciences ; Supported in part by the Bai Ren Ji Hua fund of the Chinese Academy of Sciences
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收录类别	SCI
语种	英语
资助者	Supported in part by the Bai Ren Ji Hua fund of the Chinese Academy of Sciences ; Supported in part by the Bai Ren Ji Hua fund of the Chinese Academy of Sciences ; Supported in part by the Bai Ren Ji Hua fund of the Chinese Academy of Sciences ; Supported in part by the Bai Ren Ji Hua fund of the Chinese Academy of Sciences
文献类型	期刊论文
条目标识符	http://ir.kiz.ac.cn/handle/152453/2003
专题	遗传资源与进化国家重点实验室_保护遗传学(细胞库)
通讯作者	fy@mole.bio.cam.ac.uk
作者单位	1.Kunming Institute of Zoology, The Chinese Academy of Sciences, Kunming, Yunnan (Peoples Republic of China) 2.Centre for Veterinary Science, Department of Clinical Veterinary Medicine, University of Cambridge, Cambridge (UK)
推荐引用方式 GB/T 7714	Nie W,Rens W,Wang J,et al. Conserved chromosome segments in Hylobates hoolock revealed by human and H-leucogenys paint probes[J]. CYTOGENETICS AND CELL GENETICS,2001,92(3-4):248-253.
APA	Nie W,Rens W,Wang J,Yang F*,&fy@mole.bio.cam.ac.uk.(2001).Conserved chromosome segments in Hylobates hoolock revealed by human and H-leucogenys paint probes.CYTOGENETICS AND CELL GENETICS,92(3-4),248-253.
MLA	Nie W,et al."Conserved chromosome segments in Hylobates hoolock revealed by human and H-leucogenys paint probes".CYTOGENETICS AND CELL GENETICS 92.3-4(2001):248-253.

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