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African origin of modern humans in East Asia: A tale of 12,000 Y chromosomes
Ke YH1; Su B1,2,3; Song XF1; Lu DR1; Chen LF1; Li HY1; Qi CJ1; Marzuki S4; Deka R5; Underhill P6; Xiao CJ7; Shriver M8; Lell J9; Wallace D9; Wells mRS10; Seielstad M11; Oefner P6; Zhu DL12; Jin JZ1; Huang W12,13; Chakraborty R3; Chen Z12,13; Jin L*1,3,13
2001
发表期刊SCIENCE
ISSN0036-8075
卷号292期号:5519页码:1151-1153
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摘要

To test the hypotheses of modern human origin in East Asia, we sampled 12,127 male individuals from 163 populations and typed for three Y chromosome biallelic markers (YAP, M89, and M130). All the individuals carried a mutation at one of the three sites. These three mutations (YAP+, M89T, and M130T) coalesce to another mutation (M168T), which originated in Africa about 35,000 to 89,000 years ago. Therefore, the data do not support even a minimal in situ hominid contribution in the origin of anatomically modern humans in East Asia.

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收录类别SCI
语种英语
文献类型期刊论文
条目标识符http://ir.kiz.ac.cn/handle/152453/2099
专题科研部门_比较基因组学(宿兵)
作者单位1.State Key Laboratory of Genetic Engineering, Insti- tute of Genetics, School of Life Sciences, Fudan Uni- versity, 220 Handan Road, Shanghai, China 200443, and Morgan-Tan International Center for Life Scienc- es, Shanghai, China
2.Kunming Institute of Zoology, the Chinese Academy of Sciences, Kunming, China
3.Human Genetics Center, University of Texas–Hous- ton, 1200 Herman Pressler E547, Houston, TX 77030, USA
4.Eijkman Institute for Molecular Biology, Jakarta, Indonesia
5.Department of Environmental Health, University of Cincinnati, Cincinnati, OH 45267, USA
6.Department of Genetics, Stanford University, Stan- ford, CA 94305, USA
7.Department of Biology, Yunnan University, Kunming, China
8.Department of Anthro- pology, Pennsylvania State University, University Park, PA 16802, USA
9.Center for Molecular Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA
10.Wellcome Trust Center for Human Genetics, University of Oxford, UK
11.Program for Population Genetics, Harvard School of Public Health, Boston, MA 02115, USA.
12.hanghai Second Medical University, Shanghai, China
13.National Human Genome Center at Shanghai, China
推荐引用方式
GB/T 7714
Ke YH,Su B,Song XF,et al. African origin of modern humans in East Asia: A tale of 12,000 Y chromosomes[J]. SCIENCE,2001,292(5519):1151-1153.
APA Ke YH.,Su B.,Song XF.,Lu DR.,Chen LF.,...&Jin L*.(2001).African origin of modern humans in East Asia: A tale of 12,000 Y chromosomes.SCIENCE,292(5519),1151-1153.
MLA Ke YH,et al."African origin of modern humans in East Asia: A tale of 12,000 Y chromosomes".SCIENCE 292.5519(2001):1151-1153.
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