| Insight into human sex ratio imbalance: the more boys born, the more infertile men | |
| Cheng HH1; Shang X1; He Y1; Zhang T1; Zhang YP2; Zhou RJ*1 | |
| 2007 | |
| 发表期刊 | REPRODUCTIVE BIOMEDICINE ONLINE
 |
| ISSN | 1472-6483 |
| 卷号 | 15期号:5页码:487-494 |
| 摘要 | This study investigated, through large-scale statistical analysis of the global population, whether the human sex ratio is skewing worldwide, and if so, why and how it shifts, and the impact of any shift on human reproduction. A significant imbalance of the sex ratio was observed in the whole human population, resulting in a vicious circle where the more boys born, the more infertile men occur as a consequence of the adjustment of the human sex ratio. It is proposed that both accelerated degeneration of the Y chromosome and dynamically differential fertilization of the egg by the X- and Y-bearing spermatozoa may contribute to the changing structure of the human population, suggesting a potential selection pressure favouring an alternative sex-determining/differentiation system for the human species: the DMRT] gene on the autosome may tend to replace the SRY gene on tile Y chromosome as a master sex-determining gene during evolution. These viewpoints may open a debate on the future of the human race, and assist in guiding diagnostic, prognostic and preventive treatments of human infertility and in defining population policy. |
| 关键词 | Adaptation Evolution Male Infertility Population |
| 资助者 | The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. |
| URL | 查看原文 |
| 语种 | 英语 |
| 资助者 | The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. ; The work was supported by the National Natural Science Foundation of China, the National Key Basic Research project (2006CB102103), the Program for New Century Excellent Talents in University and the 111 project #B06018. |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kiz.ac.cn/handle/152453/4233 |
| 专题 | 科研部门_分子进化与基因组多样性（张亚平） 细胞与分子进化开放实验室 |
| 作者单位 | 1.Department of Genetics and Centre for Developmental Biology, College of Life Sciences, Wuhan University, Wuhan 430072 2.Laboratory of Cellular and Molecular Evolution, Kunming Institute of Zoology, the Chinese Academy of Sciences, Kunming 650223, People’s Republic of China |
| 推荐引用方式 GB/T 7714 | Cheng HH,Shang X,He Y,et al. Insight into human sex ratio imbalance: the more boys born, the more infertile men[J]. REPRODUCTIVE BIOMEDICINE ONLINE,2007,15(5):487-494. |
| APA | Cheng HH,Shang X,He Y,Zhang T,Zhang YP,&Zhou RJ*.(2007).Insight into human sex ratio imbalance: the more boys born, the more infertile men.REPRODUCTIVE BIOMEDICINE ONLINE,15(5),487-494. |
| MLA | Cheng HH,et al."Insight into human sex ratio imbalance: the more boys born, the more infertile men".REPRODUCTIVE BIOMEDICINE ONLINE 15.5(2007):487-494. |
| 条目包含的文件 | ||||||
| 文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
| 200715487.pdf（793KB） | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | 请求全文 | |
| 个性服务 |
| 推荐该条目 |
| 保存到收藏夹 |
| 查看访问统计 |
| 导出为Endnote文件 |
| 谷歌学术 |
| 谷歌学术中相似的文章 |
| [Cheng HH]的文章 |
| [Shang X]的文章 |
| [He Y]的文章 |
| 百度学术 |
| 百度学术中相似的文章 |
| [Cheng HH]的文章 |
| [Shang X]的文章 |
| [He Y]的文章 |
| 必应学术 |
| 必应学术中相似的文章 |
| [Cheng HH]的文章 |
| [Shang X]的文章 |
| [He Y]的文章 |
| 相关权益政策 |
| 暂无数据 |
| 收藏/分享 |
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。
修改评论