| Lancifodilactone F: A novel nortriterpenoid possessing a unique skeleton from Schisandra lancifolia and its anti-HIV activity | |
| Xiao WL1,2; Li RT1; Li SH1; Li XL1,2; Sun HD*1; Zheng YT3; Wang RR2,3; Lu Y4; Wang C4; Zheng QT4; hdsun@mail.kib.ac.cn | |
| 2005 | |
| 发表期刊 | ORGANIC LETTERS
 |
| ISSN | 1523-7060 |
| 卷号 | 7期号:7页码:1263-1266 |
| 合作性质 | 其它 |
| 摘要 | Lancifodilactone F (1), possessing an unprecedented rearranged pentanortriterpenoid backbone derived from cycloartane, was isolated from the leaves and stems of Schisandra lancifolia (Rehd. et Wils) A. C. Smith. Its structure was established by comprehensive NMR and MS spectroscopic analysis, coupled with single-crystal X-ray experiment. Compound 1 exerted minimal cytotoxicity against C8166 cells (CC50 > 200 mu g/mL) and showed anti-HIV activity with EC50 = 20.69 +/- 3.31 mu g/mL and a selectivity index > 6.62. |
| 资助者 | This project was supported by grants from the National Natural Science Foundation of China (No. 20402016, awarded to Dr. Rong-Tao Li). ; This project was supported by grants from the National Natural Science Foundation of China (No. 20402016, awarded to Dr. Rong-Tao Li). ; This project was supported by grants from the National Natural Science Foundation of China (No. 20402016, awarded to Dr. Rong-Tao Li). ; This project was supported by grants from the National Natural Science Foundation of China (No. 20402016, awarded to Dr. Rong-Tao Li). |
| URL | 查看原文 |
| 收录类别 | SCI |
| 语种 | 英语 |
| 资助者 | This project was supported by grants from the National Natural Science Foundation of China (No. 20402016, awarded to Dr. Rong-Tao Li). ; This project was supported by grants from the National Natural Science Foundation of China (No. 20402016, awarded to Dr. Rong-Tao Li). ; This project was supported by grants from the National Natural Science Foundation of China (No. 20402016, awarded to Dr. Rong-Tao Li). ; This project was supported by grants from the National Natural Science Foundation of China (No. 20402016, awarded to Dr. Rong-Tao Li). |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kiz.ac.cn/handle/152453/4549 |
| 专题 | 科研部门_分子免疫药理学（郑永唐） |
| 通讯作者 | hdsun@mail.kib.ac.cn |
| 作者单位 | 1.State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, Yunnan, P. R. China 2.Graduate School of the Chinese Academy of Sciences, Beijing 10039, P. R. China 3.Laboratory of Molecular Immunopharmacology, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, Yunnan, P. R. China 4.Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing 100050, P. R. China |
| 推荐引用方式 GB/T 7714 | Xiao WL,Li RT,Li SH,et al. Lancifodilactone F: A novel nortriterpenoid possessing a unique skeleton from Schisandra lancifolia and its anti-HIV activity[J]. ORGANIC LETTERS,2005,7(7):1263-1266. |
| APA | Xiao WL.,Li RT.,Li SH.,Li XL.,Sun HD*.,...&hdsun@mail.kib.ac.cn.(2005).Lancifodilactone F: A novel nortriterpenoid possessing a unique skeleton from Schisandra lancifolia and its anti-HIV activity.ORGANIC LETTERS,7(7),1263-1266. |
| MLA | Xiao WL,et al."Lancifodilactone F: A novel nortriterpenoid possessing a unique skeleton from Schisandra lancifolia and its anti-HIV activity".ORGANIC LETTERS 7.7(2005):1263-1266. |
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