Rubriflordilactones A and B, two novel bisnortriterpenoids from Schisandra rubriflora and their biological activities

	Rubriflordilactones A and B, two novel bisnortriterpenoids from Schisandra rubriflora and their biological activities
	Xiao WL 1; Yang LM 2; Gong NB 3; Wu L 3; Wang RR 2; Pu JX 1,4; Li XL 1,4; Huang SX 1,4; Zheng YT 2; Li RT 1; Lu Y 3; Zheng QT 3; Sun HD*1; hdsun@mail.kib.ac.cn
	2006
发表期刊	ORGANIC LETTERS
ISSN	1523-7060
卷号	8 期号:5 页码:991-994
合作性质	其它
摘要	Rubriflordilactones A (1) and B (2), two novel highly unsaturated rearranged bisnortriterpenoids possessing a biosynthetically modified aromatic D-ring, were isolated from the leaves and stems of Schisandra rubriflora. Their structures were established on the basis of extensive spectroscopic methods, including two-dimensional NMR techniques, and confirmed by X-ray crystallographic analysis. Compound 1 showed weak anti-HIV-1 activity, and compound 2 exhibited an EC50 value of 9.75 mu g/mL (SI = 12.39) against HIV-1 replication with low cytotoxicity.
资助者	This project was supported by grants from the Natural Science Foundation of Yunnan Province (no. 2005XY04), the National Natural Science Foundation of China (no. 20402016), and Key Scientific and Techno- logical projects of China (2004BA719A14) and Yunnan Province (2004NG12). ; This project was supported by grants from the Natural Science Foundation of Yunnan Province (no. 2005XY04), the National Natural Science Foundation of China (no. 20402016), and Key Scientific and Techno- logical projects of China (2004BA719A14) and Yunnan Province (2004NG12). ; This project was supported by grants from the Natural Science Foundation of Yunnan Province (no. 2005XY04), the National Natural Science Foundation of China (no. 20402016), and Key Scientific and Techno- logical projects of China (2004BA719A14) and Yunnan Province (2004NG12). ; This project was supported by grants from the Natural Science Foundation of Yunnan Province (no. 2005XY04), the National Natural Science Foundation of China (no. 20402016), and Key Scientific and Techno- logical projects of China (2004BA719A14) and Yunnan Province (2004NG12).
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收录类别	SCI
语种	英语
资助者	This project was supported by grants from the Natural Science Foundation of Yunnan Province (no. 2005XY04), the National Natural Science Foundation of China (no. 20402016), and Key Scientific and Techno- logical projects of China (2004BA719A14) and Yunnan Province (2004NG12). ; This project was supported by grants from the Natural Science Foundation of Yunnan Province (no. 2005XY04), the National Natural Science Foundation of China (no. 20402016), and Key Scientific and Techno- logical projects of China (2004BA719A14) and Yunnan Province (2004NG12). ; This project was supported by grants from the Natural Science Foundation of Yunnan Province (no. 2005XY04), the National Natural Science Foundation of China (no. 20402016), and Key Scientific and Techno- logical projects of China (2004BA719A14) and Yunnan Province (2004NG12). ; This project was supported by grants from the Natural Science Foundation of Yunnan Province (no. 2005XY04), the National Natural Science Foundation of China (no. 20402016), and Key Scientific and Techno- logical projects of China (2004BA719A14) and Yunnan Province (2004NG12).
文献类型	期刊论文
条目标识符	http://ir.kiz.ac.cn/handle/152453/4571
专题	科研部门_分子免疫药理学（郑永唐）科研部门_动物模型与人类重大疾病机理重点实验室
通讯作者	hdsun@mail.kib.ac.cn
作者单位	1.State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, Yunnan 2.Key Laboratory of Animal Models and Human Disease Mechanisms and Laboratory of Molecular Immunopharmacology, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, Yunnan 3.Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing 100050, P. R. Chin 4.Graduate School of the Chinese Academy of Sciences, Beijing 100039, P. R. China
推荐引用方式 GB/T 7714	Xiao WL,Yang LM,Gong NB,et al. Rubriflordilactones A and B, two novel bisnortriterpenoids from Schisandra rubriflora and their biological activities[J]. ORGANIC LETTERS,2006,8(5):991-994.
APA	Xiao WL.,Yang LM.,Gong NB.,Wu L.,Wang RR.,...&hdsun@mail.kib.ac.cn.(2006).Rubriflordilactones A and B, two novel bisnortriterpenoids from Schisandra rubriflora and their biological activities.ORGANIC LETTERS,8(5),991-994.
MLA	Xiao WL,et al."Rubriflordilactones A and B, two novel bisnortriterpenoids from Schisandra rubriflora and their biological activities".ORGANIC LETTERS 8.5(2006):991-994.

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