| Nortriterpenoids and lignans from Schisandra sphenanthera | |
| Xiao WL1; Huang SX1; Wang RR2; Zhong JL3; Gao XM1; He F1; Pu JX1; Lu Y3; Zheng YT2; Zheng QT3; Sun HD*1; hdsun@mail.kib.ac.cn | |
| 2008 | |
| 发表期刊 | PHYTOCHEMISTRY
 |
| ISSN | 0031-9422 |
| 卷号 | 69期号:16页码:2862-2866 |
| 合作性质 | 其它 |
| 摘要 | Nortriterpenoids, sphenadilactone C (1) and sphenasin A (2), together with four known lignans (3-6), were isolated from the leaves and stems of Schisandra sphenanthera. Their structures were elucidated by extensive analysis of 1D and 2D NMR spectroscopic data and compound 2 was further confirmed by single-crystal X-ray diffraction. Compound 1 features a partial enol moiety and an acetamide group in its structure. In addition, compounds 1. 3-6 showed weak anti-HIV-1 activity with EC(50) values in the range of 15.5-29.5 mu g/mL. |
| 关键词 | Schisandra Sphenanthera Schisandraceae Nortriterpenoid Lignans Anti-hiv-1 Activity |
| 资助者 | This project was supported by grants from the Chinese Acad- emy of Sciences projects (XiBuZhiGuang to Wei-Lie Xiao and No. KSCX1-YW-R-24), the Yong Academic and Technical Leader Raising Foundation of Yunnan Province (2006PY01-47), the Natu- ral Science Foundation of Yunnan Province (2005XY04 and 2006B0042Q), Key Scientific and Technological project of China (2004BA719A14), and the National Natural Science Foundation of China (30830115 and 20802082). ; This project was supported by grants from the Chinese Acad- emy of Sciences projects (XiBuZhiGuang to Wei-Lie Xiao and No. KSCX1-YW-R-24), the Yong Academic and Technical Leader Raising Foundation of Yunnan Province (2006PY01-47), the Natu- ral Science Foundation of Yunnan Province (2005XY04 and 2006B0042Q), Key Scientific and Technological project of China (2004BA719A14), and the National Natural Science Foundation of China (30830115 and 20802082). ; This project was supported by grants from the Chinese Acad- emy of Sciences projects (XiBuZhiGuang to Wei-Lie Xiao and No. KSCX1-YW-R-24), the Yong Academic and Technical Leader Raising Foundation of Yunnan Province (2006PY01-47), the Natu- ral Science Foundation of Yunnan Province (2005XY04 and 2006B0042Q), Key Scientific and Technological project of China (2004BA719A14), and the National Natural Science Foundation of China (30830115 and 20802082). ; This project was supported by grants from the Chinese Acad- emy of Sciences projects (XiBuZhiGuang to Wei-Lie Xiao and No. KSCX1-YW-R-24), the Yong Academic and Technical Leader Raising Foundation of Yunnan Province (2006PY01-47), the Natu- ral Science Foundation of Yunnan Province (2005XY04 and 2006B0042Q), Key Scientific and Technological project of China (2004BA719A14), and the National Natural Science Foundation of China (30830115 and 20802082). |
| URL | 查看原文 |
| 资助者 | This project was supported by grants from the Chinese Acad- emy of Sciences projects (XiBuZhiGuang to Wei-Lie Xiao and No. KSCX1-YW-R-24), the Yong Academic and Technical Leader Raising Foundation of Yunnan Province (2006PY01-47), the Natu- ral Science Foundation of Yunnan Province (2005XY04 and 2006B0042Q), Key Scientific and Technological project of China (2004BA719A14), and the National Natural Science Foundation of China (30830115 and 20802082). ; This project was supported by grants from the Chinese Acad- emy of Sciences projects (XiBuZhiGuang to Wei-Lie Xiao and No. KSCX1-YW-R-24), the Yong Academic and Technical Leader Raising Foundation of Yunnan Province (2006PY01-47), the Natu- ral Science Foundation of Yunnan Province (2005XY04 and 2006B0042Q), Key Scientific and Technological project of China (2004BA719A14), and the National Natural Science Foundation of China (30830115 and 20802082). ; This project was supported by grants from the Chinese Acad- emy of Sciences projects (XiBuZhiGuang to Wei-Lie Xiao and No. KSCX1-YW-R-24), the Yong Academic and Technical Leader Raising Foundation of Yunnan Province (2006PY01-47), the Natu- ral Science Foundation of Yunnan Province (2005XY04 and 2006B0042Q), Key Scientific and Technological project of China (2004BA719A14), and the National Natural Science Foundation of China (30830115 and 20802082). ; This project was supported by grants from the Chinese Acad- emy of Sciences projects (XiBuZhiGuang to Wei-Lie Xiao and No. KSCX1-YW-R-24), the Yong Academic and Technical Leader Raising Foundation of Yunnan Province (2006PY01-47), the Natu- ral Science Foundation of Yunnan Province (2005XY04 and 2006B0042Q), Key Scientific and Technological project of China (2004BA719A14), and the National Natural Science Foundation of China (30830115 and 20802082). |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kiz.ac.cn/handle/152453/4613 |
| 专题 | 科研部门_分子免疫药理学（郑永唐） 科研部门_动物模型与人类重大疾病机理重点实验室 |
| 通讯作者 | hdsun@mail.kib.ac.cn |
| 作者单位 | 1.State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, Yunnan, PR China 2.Key Laboratory of Animal Models and Human Disease Mechanisms and Laboratory of Molecular Immunopharmacology, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, Yunnan, PR China 3.Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing 100050, PR China |
| 推荐引用方式 GB/T 7714 | Xiao WL,Huang SX,Wang RR,et al. Nortriterpenoids and lignans from Schisandra sphenanthera[J]. PHYTOCHEMISTRY,2008,69(16):2862-2866. |
| APA | Xiao WL.,Huang SX.,Wang RR.,Zhong JL.,Gao XM.,...&hdsun@mail.kib.ac.cn.(2008).Nortriterpenoids and lignans from Schisandra sphenanthera.PHYTOCHEMISTRY,69(16),2862-2866. |
| MLA | Xiao WL,et al."Nortriterpenoids and lignans from Schisandra sphenanthera".PHYTOCHEMISTRY 69.16(2008):2862-2866. |
| 条目包含的文件 | ||||||
| 文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
| 2008692862.pdf（353KB） | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | 请求全文 | |
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。
修改评论