Three new compounds from Kadsura longipedunculata

	Three new compounds from Kadsura longipedunculata
	Pu JX 1; Gao XM 1; Lei C 1; Xiao WL 1; Wang RR 2; Yang LB 1; Zhao Y 1; Li LM 1; Huang SX 1; Zheng YT 2; Sun HD*1; hdsun@mail.kib.ac.cn
	2008
发表期刊	CHEMICAL & PHARMACEUTICAL BULLETIN
ISSN	0009-2363
卷号	56 期号:8 页码:1143-1146
合作性质	其它
摘要	Two new tetrahydrofuran lignans, kadlongirins A and B (1, 2), a new cadinane-type sesquiterpenoid, 2,7-dihydroxy-1 1,1 2-dehydrocalamenene (3), together with seven known lignans, grandisin, fragransin B-1, vladirol F, kadsuralignan C, otobaphenol, isoanwulignan, and 4-[4-(3,4-dimethoxyphenyl)-2,3-dimethylbutyl]-2-methoxyphenol, were isolated from the leaves and stems of Kadsura longipedunculata. The structures of these new compounds were elucidated by spectroscopic methods. Compound 2 exhibited weak anti-human immunodeficiency virus-1 activity with an EC50 value of 16.0 mu g/ml, and therapeutic index (TI) value of 6.7.
关键词	Kadsura Longipedunculata Lignan Sesquiterpenoid Anti-human Immunodeficiency Virus Activity
资助者	We gratefully acknowledge the support of the Natural Science Foundation of Yunnan Province (2005XY04 and 2006B0042Q), the Western Doctoral Foundation of Chinese Academy of Sciences (presided by J.-X. Pu), and the key Scientific and Technological projects of Yunnan province (2004NG12, 2005B0048M). ; We gratefully acknowledge the support of the Natural Science Foundation of Yunnan Province (2005XY04 and 2006B0042Q), the Western Doctoral Foundation of Chinese Academy of Sciences (presided by J.-X. Pu), and the key Scientific and Technological projects of Yunnan province (2004NG12, 2005B0048M). ; We gratefully acknowledge the support of the Natural Science Foundation of Yunnan Province (2005XY04 and 2006B0042Q), the Western Doctoral Foundation of Chinese Academy of Sciences (presided by J.-X. Pu), and the key Scientific and Technological projects of Yunnan province (2004NG12, 2005B0048M). ; We gratefully acknowledge the support of the Natural Science Foundation of Yunnan Province (2005XY04 and 2006B0042Q), the Western Doctoral Foundation of Chinese Academy of Sciences (presided by J.-X. Pu), and the key Scientific and Technological projects of Yunnan province (2004NG12, 2005B0048M).
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收录类别	SCI
语种	英语
资助者	We gratefully acknowledge the support of the Natural Science Foundation of Yunnan Province (2005XY04 and 2006B0042Q), the Western Doctoral Foundation of Chinese Academy of Sciences (presided by J.-X. Pu), and the key Scientific and Technological projects of Yunnan province (2004NG12, 2005B0048M). ; We gratefully acknowledge the support of the Natural Science Foundation of Yunnan Province (2005XY04 and 2006B0042Q), the Western Doctoral Foundation of Chinese Academy of Sciences (presided by J.-X. Pu), and the key Scientific and Technological projects of Yunnan province (2004NG12, 2005B0048M). ; We gratefully acknowledge the support of the Natural Science Foundation of Yunnan Province (2005XY04 and 2006B0042Q), the Western Doctoral Foundation of Chinese Academy of Sciences (presided by J.-X. Pu), and the key Scientific and Technological projects of Yunnan province (2004NG12, 2005B0048M). ; We gratefully acknowledge the support of the Natural Science Foundation of Yunnan Province (2005XY04 and 2006B0042Q), the Western Doctoral Foundation of Chinese Academy of Sciences (presided by J.-X. Pu), and the key Scientific and Technological projects of Yunnan province (2004NG12, 2005B0048M).
文献类型	期刊论文
条目标识符	http://ir.kiz.ac.cn/handle/152453/4625
专题	科研部门_分子免疫药理学（郑永唐）科研部门_动物模型与人类重大疾病机理重点实验室
通讯作者	hdsun@mail.kib.ac.cn
作者单位	1.State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences; Kunming 650204, P. R. China 2.Laboratory of Molecular Immunopharmacology, Key Laboratory of Animal Models and Human Disease Mechanisms, Kunming Institute of Zoology, Chinese Academy of Sciences; Kunming 650223, Yunnan, P. R. China
推荐引用方式 GB/T 7714	Pu JX,Gao XM,Lei C,et al. Three new compounds from Kadsura longipedunculata[J]. CHEMICAL & PHARMACEUTICAL BULLETIN,2008,56(8):1143-1146.
APA	Pu JX.,Gao XM.,Lei C.,Xiao WL.,Wang RR.,...&hdsun@mail.kib.ac.cn.(2008).Three new compounds from Kadsura longipedunculata.CHEMICAL & PHARMACEUTICAL BULLETIN,56(8),1143-1146.
MLA	Pu JX,et al."Three new compounds from Kadsura longipedunculata".CHEMICAL & PHARMACEUTICAL BULLETIN 56.8(2008):1143-1146.

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