Chemical Constituents from the Leaves and Stems of Schisandra rubriflora

	Chemical Constituents from the Leaves and Stems of Schisandra rubriflora
	Xiao WL 1; Yang SY 2; Yang LM 3; Yang GY 1; Wang RR 3; Zhang HB 1,4; Zhao W 1,4; Pu JX 1; Lu Y 2; Zheng YT 3; Sun HD*1; hdsun@mail.kib.ac.cn
	2010
发表期刊	JOURNAL OF NATURAL PRODUCTS
ISSN	0163-3864
卷号	73 期号:2 页码:221-225
合作性质	其它
摘要	Six new nortriterpenoids, schirubridilactones A-F (1-6). as well as 14 known compounds, were isolated from the leaves and stems of Schisandra rubriflora. The Structures of 1-6 were elucidated oil the basis of spectroscopic methods including HSQC, HMBC, (1)H-(1)H COSY, and ROESY NMR experiments. The relative stereochemistry of I was confirmed through single-crystal X-ray analysis. In addition, compounds 1-6 showed anti-HIV-1 activity with EC(50) values in the range 14.3-80.8 mu g/mL and Selectivity indices in the range 2.2-9.0.
资助者	This project was supported financially by the NSFC (No. 20802082 and 30830115) and funds from the Chinese Academy of Sciences (“Xibuzhiguang” to W.-L.X and No. KSCX1- YW-R-24), the Major State Basic Research Development Program of China (Nos. 2009CB522303 and 2009CB940900), the Young Academic and Technical Leader Rising Foundation of Yunnan Province (2006PY01- 47), and the Natural Science Foundation of Yunnan Province (2005XY04 and 2006B0042Q). ; This project was supported financially by the NSFC (No. 20802082 and 30830115) and funds from the Chinese Academy of Sciences (“Xibuzhiguang” to W.-L.X and No. KSCX1- YW-R-24), the Major State Basic Research Development Program of China (Nos. 2009CB522303 and 2009CB940900), the Young Academic and Technical Leader Rising Foundation of Yunnan Province (2006PY01- 47), and the Natural Science Foundation of Yunnan Province (2005XY04 and 2006B0042Q). ; This project was supported financially by the NSFC (No. 20802082 and 30830115) and funds from the Chinese Academy of Sciences (“Xibuzhiguang” to W.-L.X and No. KSCX1- YW-R-24), the Major State Basic Research Development Program of China (Nos. 2009CB522303 and 2009CB940900), the Young Academic and Technical Leader Rising Foundation of Yunnan Province (2006PY01- 47), and the Natural Science Foundation of Yunnan Province (2005XY04 and 2006B0042Q). ; This project was supported financially by the NSFC (No. 20802082 and 30830115) and funds from the Chinese Academy of Sciences (“Xibuzhiguang” to W.-L.X and No. KSCX1- YW-R-24), the Major State Basic Research Development Program of China (Nos. 2009CB522303 and 2009CB940900), the Young Academic and Technical Leader Rising Foundation of Yunnan Province (2006PY01- 47), and the Natural Science Foundation of Yunnan Province (2005XY04 and 2006B0042Q).
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收录类别	SCI
资助者	This project was supported financially by the NSFC (No. 20802082 and 30830115) and funds from the Chinese Academy of Sciences (“Xibuzhiguang” to W.-L.X and No. KSCX1- YW-R-24), the Major State Basic Research Development Program of China (Nos. 2009CB522303 and 2009CB940900), the Young Academic and Technical Leader Rising Foundation of Yunnan Province (2006PY01- 47), and the Natural Science Foundation of Yunnan Province (2005XY04 and 2006B0042Q). ; This project was supported financially by the NSFC (No. 20802082 and 30830115) and funds from the Chinese Academy of Sciences (“Xibuzhiguang” to W.-L.X and No. KSCX1- YW-R-24), the Major State Basic Research Development Program of China (Nos. 2009CB522303 and 2009CB940900), the Young Academic and Technical Leader Rising Foundation of Yunnan Province (2006PY01- 47), and the Natural Science Foundation of Yunnan Province (2005XY04 and 2006B0042Q). ; This project was supported financially by the NSFC (No. 20802082 and 30830115) and funds from the Chinese Academy of Sciences (“Xibuzhiguang” to W.-L.X and No. KSCX1- YW-R-24), the Major State Basic Research Development Program of China (Nos. 2009CB522303 and 2009CB940900), the Young Academic and Technical Leader Rising Foundation of Yunnan Province (2006PY01- 47), and the Natural Science Foundation of Yunnan Province (2005XY04 and 2006B0042Q). ; This project was supported financially by the NSFC (No. 20802082 and 30830115) and funds from the Chinese Academy of Sciences (“Xibuzhiguang” to W.-L.X and No. KSCX1- YW-R-24), the Major State Basic Research Development Program of China (Nos. 2009CB522303 and 2009CB940900), the Young Academic and Technical Leader Rising Foundation of Yunnan Province (2006PY01- 47), and the Natural Science Foundation of Yunnan Province (2005XY04 and 2006B0042Q).
文献类型	期刊论文
条目标识符	http://ir.kiz.ac.cn/handle/152453/4703
专题	科研部门_分子免疫药理学（郑永唐）科研部门_动物模型与人类重大疾病机理重点实验室
通讯作者	hdsun@mail.kib.ac.cn
作者单位	1.State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, Yunnan, People’s Republic of China 2.Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Peking 100050, People’s Republic of China 3.Key Laboratory of Animal Models and Human Disease Mechanisms and Laboratory of Molecular Immunopharmacology, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, Yunnan, People’s Republic of China 4.Graduate School of the Chinese Academy of Sciences, Beijing 100039, People’s Republic of China
推荐引用方式 GB/T 7714	Xiao WL,Yang SY,Yang LM,et al. Chemical Constituents from the Leaves and Stems of Schisandra rubriflora[J]. JOURNAL OF NATURAL PRODUCTS,2010,73(2):221-225.
APA	Xiao WL.,Yang SY.,Yang LM.,Yang GY.,Wang RR.,...&hdsun@mail.kib.ac.cn.(2010).Chemical Constituents from the Leaves and Stems of Schisandra rubriflora.JOURNAL OF NATURAL PRODUCTS,73(2),221-225.
MLA	Xiao WL,et al."Chemical Constituents from the Leaves and Stems of Schisandra rubriflora".JOURNAL OF NATURAL PRODUCTS 73.2(2010):221-225.

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