More evidence for non-maternal inheritance of mitochondrial DNA?

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	More evidence for non-maternal inheritance of mitochondrial DNA?
	Bandelt HJ*1; Kong QP 2; Parson W 3; Salas A 4; bandelt@math.uni-hamburg.de
	2005
发表期刊	JOURNAL OF MEDICAL GENETICS
ISSN	0022-2593
卷号	42 期号:12 页码:957-960
合作性质	其它
摘要	Background: A single case of paternal co-transmission ofmitochondrial DNA (mtDNA) in humans has been reported so far. Objective: To find potential instances of non-maternal inheritance of mtDNA. Methods: Published medical case studies (of single patients) were searched for irregular mtDNA patterns by comparing the given haplotype information for different clones or tissues with the worldwide mtDNA database as known to date-a method that has proved robust and reliable for the detection of flawed mtDNA sequence data. Results: More than 20 studies were found reporting clear cut instances with mtDNAs of different ancestries in single individuals. As examples, cases are reviewed from recent published reports which, at face value, may be taken as evidence for paternal inheritance of mtDNA or recombination. Conclusions: Multiple types (or recombinant types) of quite dissimilar mitochondrial DNA from different parts of the known mtDNA phylogeny are often reported in single individuals. From re-analyses and corrigenda of forensic mtDNA data, it is apparent that the phenomenon of mixed or mosaic mtDNA can be ascribed solely to contamination and sample mix up.
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收录类别	SCI
语种	英语
文献类型	期刊论文
条目标识符	http://ir.kiz.ac.cn/handle/152453/4773
专题	科研部门_分子人类学（孔庆鹏）细胞与分子进化重点实验室
通讯作者	bandelt@math.uni-hamburg.de
作者单位	1.Fachbereich Mathematik, Universita ¨t Hamburg, Hamburg, Germany 2.Key Laboratory of Cellular and Molecular Evolution and Molecular Biology of Domestic Animals, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China 3.nstitute of Legal Medicine, Innsbruck Medical University, Innsbruck, Austria 4.Unidad de Gene ´tica, Instituto de Medicina Legal, Facultad de Medicina, Santiago de Compostela, Galicia, Spain
推荐引用方式 GB/T 7714	Bandelt HJ*,Kong QP,Parson W,et al. More evidence for non-maternal inheritance of mitochondrial DNA?[J]. JOURNAL OF MEDICAL GENETICS,2005,42(12):957-960.
APA	Bandelt HJ*,Kong QP,Parson W,Salas A,&bandelt@math.uni-hamburg.de.(2005).More evidence for non-maternal inheritance of mitochondrial DNA?.JOURNAL OF MEDICAL GENETICS,42(12),957-960.
MLA	Bandelt HJ*,et al."More evidence for non-maternal inheritance of mitochondrial DNA?".JOURNAL OF MEDICAL GENETICS 42.12(2005):957-960.

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