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Identification of protein superfamily from structure-based sequence motif
Huang JF*; Liu CQ; jfhuang@pulic.km.yn.cn
2002
发表期刊CHINESE SCIENCE BULLETIN
ISSN1001-6538
卷号47期号:16页码:1377-1381
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摘要The structure-based sequence motif of the distant proteins in evolution, protein tyrosine phosphatases (PTP) I and II superfamilies, as an example, has been defined by the structural comparison, structure-based sequence alignment and analyses on substitution patterns of residues in common sequence conserved regions. And the phosphatases I and II can be correctly identified together by the structure-based PTP sequence motif from SWISS-PROT and TrEBML databases. The results show that the correct rates of identification are over 98%. This is the first time to identify PTP I and II together by this motif.
关键词Protein Tyrosine Phosphatases Sequence Motif Sequence Identification Of Superfamily Hypothetical Proteins Molecular Evolution
资助者This work was supported by the National Natural Science Foundation of China (Grant Nos. 30170507 and 30024004) and the Natural Science Foundation of Yunnan Province (Grant Nos. 98C007R and 1999C0084M). ; This work was supported by the National Natural Science Foundation of China (Grant Nos. 30170507 and 30024004) and the Natural Science Foundation of Yunnan Province (Grant Nos. 98C007R and 1999C0084M). ; This work was supported by the National Natural Science Foundation of China (Grant Nos. 30170507 and 30024004) and the Natural Science Foundation of Yunnan Province (Grant Nos. 98C007R and 1999C0084M). ; This work was supported by the National Natural Science Foundation of China (Grant Nos. 30170507 and 30024004) and the Natural Science Foundation of Yunnan Province (Grant Nos. 98C007R and 1999C0084M).
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收录类别SCI
语种英语
资助者This work was supported by the National Natural Science Foundation of China (Grant Nos. 30170507 and 30024004) and the Natural Science Foundation of Yunnan Province (Grant Nos. 98C007R and 1999C0084M). ; This work was supported by the National Natural Science Foundation of China (Grant Nos. 30170507 and 30024004) and the Natural Science Foundation of Yunnan Province (Grant Nos. 98C007R and 1999C0084M). ; This work was supported by the National Natural Science Foundation of China (Grant Nos. 30170507 and 30024004) and the Natural Science Foundation of Yunnan Province (Grant Nos. 98C007R and 1999C0084M). ; This work was supported by the National Natural Science Foundation of China (Grant Nos. 30170507 and 30024004) and the Natural Science Foundation of Yunnan Province (Grant Nos. 98C007R and 1999C0084M).
文献类型期刊论文
条目标识符http://ir.kiz.ac.cn/handle/152453/4893
专题结构生物信息学
细胞与分子进化重点实验室
通讯作者jfhuang@pulic.km.yn.cn
作者单位Key Laboratory of Cellular and Molecular Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China
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Huang JF*,Liu CQ,jfhuang@pulic.km.yn.cn. Identification of protein superfamily from structure-based sequence motif[J]. CHINESE SCIENCE BULLETIN,2002,47(16):1377-1381.
APA Huang JF*,Liu CQ,&jfhuang@pulic.km.yn.cn.(2002).Identification of protein superfamily from structure-based sequence motif.CHINESE SCIENCE BULLETIN,47(16),1377-1381.
MLA Huang JF*,et al."Identification of protein superfamily from structure-based sequence motif".CHINESE SCIENCE BULLETIN 47.16(2002):1377-1381.
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