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Theoretical studies on conformation comparison of braid-like and triplex DNA
Yang LJ1; Bai CL[*]1; Liu CQ2; Shi XF2; Lee IS1; clbai@infoc3.icas.ac.cn
1999
发表期刊JOURNAL OF MOLECULAR STRUCTURE
ISSN0022-2860
卷号477期号:1-3页码:7-13
合作性质其它
摘要Based on the experimental data of scanning tunneling microscopy (STM), models of three-stranded braid-like DNAs composed by three kinds of base triplets AAA, TAT and GCA were constructed. We investigated the braid-like DNAs and their comparative tripler DNAs using a molecular mechanics method. The three strands of braid-like DNAs are proven equivalent, while those of tripler DNAs are not. The conformational energies for braid-like DNAs were found to be higher than that for tripler DNAs. Each period in one strand of braid-like DNA has 18 nucleotides, half of which are right-handed, while the other half are left-handed. Additional discussions concerning sugar puckering modes and the H-bonds are also included.
关键词Braid-like Dna Triplex Dna Conformation Molecular Mechanics
资助者The project is supported by the National Natural Science Foundation of China and the Foundation of Chinese Academy of Science. ; The project is supported by the National Natural Science Foundation of China and the Foundation of Chinese Academy of Science. ; The project is supported by the National Natural Science Foundation of China and the Foundation of Chinese Academy of Science. ; The project is supported by the National Natural Science Foundation of China and the Foundation of Chinese Academy of Science.
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收录类别SCI
资助者The project is supported by the National Natural Science Foundation of China and the Foundation of Chinese Academy of Science. ; The project is supported by the National Natural Science Foundation of China and the Foundation of Chinese Academy of Science. ; The project is supported by the National Natural Science Foundation of China and the Foundation of Chinese Academy of Science. ; The project is supported by the National Natural Science Foundation of China and the Foundation of Chinese Academy of Science.
文献类型期刊论文
条目标识符http://ir.kiz.ac.cn/handle/152453/5153
专题结构生物信息学
通讯作者clbai@infoc3.icas.ac.cn
作者单位1.Institute of Chemistry, Chinese Academy of Sciences, 100080 Beijing P. R. China
2.Kunming Institute of Zoology, Chinese Academy of Sciences, 650223 Kunming P.R.China
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GB/T 7714
Yang LJ,Bai CL[*],Liu CQ,et al. Theoretical studies on conformation comparison of braid-like and triplex DNA[J]. JOURNAL OF MOLECULAR STRUCTURE,1999,477(1-3):7-13.
APA Yang LJ,Bai CL[*],Liu CQ,Shi XF,Lee IS,&clbai@infoc3.icas.ac.cn.(1999).Theoretical studies on conformation comparison of braid-like and triplex DNA.JOURNAL OF MOLECULAR STRUCTURE,477(1-3),7-13.
MLA Yang LJ,et al."Theoretical studies on conformation comparison of braid-like and triplex DNA".JOURNAL OF MOLECULAR STRUCTURE 477.1-3(1999):7-13.
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