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The topological configuration and conformational analysis of mRNA in translation
Liu SQ1; Liu CQ*1,2; tbrg@public.km.yn.cn
2002
发表期刊CHINESE SCIENCE BULLETIN
ISSN1001-6538
卷号47期号:5页码:384-389
合作性质其它
摘要The theoretical model construction of mRNA hairpin structure and single-stranded structure as well as the simulation studies on RNA structure determined by the X-ray crystal diffraction and nuclear magnetic resonance revealed that in translation, after mRNA being unfolded into single-stranded structure, its topological configuration was closely correlative with the original hairpin structure. The conformational features of single-stranded mRNA appeared as helical regions alternating with curly regions to different extents, which might exert the influence on the folding of nascent polypeptide by various regulating effects including different translational rates.
关键词Hairpin Structure Of Narna Topological Configuration Of Single-stranded Mrna
资助者This work was supported by the National Natural Science Foundation of China (Grant No. 39770418) and the Knowledge Innovation Program of the Chinese Academy of Sciences (Grant No. KJCX 1-08). ; This work was supported by the National Natural Science Foundation of China (Grant No. 39770418) and the Knowledge Innovation Program of the Chinese Academy of Sciences (Grant No. KJCX 1-08). ; This work was supported by the National Natural Science Foundation of China (Grant No. 39770418) and the Knowledge Innovation Program of the Chinese Academy of Sciences (Grant No. KJCX 1-08). ; This work was supported by the National Natural Science Foundation of China (Grant No. 39770418) and the Knowledge Innovation Program of the Chinese Academy of Sciences (Grant No. KJCX 1-08).
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收录类别SCI
语种英语
资助者This work was supported by the National Natural Science Foundation of China (Grant No. 39770418) and the Knowledge Innovation Program of the Chinese Academy of Sciences (Grant No. KJCX 1-08). ; This work was supported by the National Natural Science Foundation of China (Grant No. 39770418) and the Knowledge Innovation Program of the Chinese Academy of Sciences (Grant No. KJCX 1-08). ; This work was supported by the National Natural Science Foundation of China (Grant No. 39770418) and the Knowledge Innovation Program of the Chinese Academy of Sciences (Grant No. KJCX 1-08). ; This work was supported by the National Natural Science Foundation of China (Grant No. 39770418) and the Knowledge Innovation Program of the Chinese Academy of Sciences (Grant No. KJCX 1-08).
文献类型期刊论文
条目标识符http://ir.kiz.ac.cn/handle/152453/5243
专题其他
通讯作者tbrg@public.km.yn.cn
作者单位1.Kunming Institute of Zoology, Chinese Academy of Sciences, Kun- ming 650223, China
2.Modern Biological Center, Yunnan University, Kunming 650091, China
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Liu SQ,Liu CQ*,tbrg@public.km.yn.cn. The topological configuration and conformational analysis of mRNA in translation[J]. CHINESE SCIENCE BULLETIN,2002,47(5):384-389.
APA Liu SQ,Liu CQ*,&tbrg@public.km.yn.cn.(2002).The topological configuration and conformational analysis of mRNA in translation.CHINESE SCIENCE BULLETIN,47(5),384-389.
MLA Liu SQ,et al."The topological configuration and conformational analysis of mRNA in translation".CHINESE SCIENCE BULLETIN 47.5(2002):384-389.
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