High prevalence of HIV-1 and hepatitis C virus coinfection among injection drug users in the southeastern region of Yunnan, China

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	High prevalence of HIV-1 and hepatitis C virus coinfection among injection drug users in the southeastern region of Yunnan, China
	Zhang CY 1; Yang RG 2; Xia XS 1; Qin SY 3; Dai JP 3; Zhang ZB 4; Peng ZZ 4; Wei T 5; Liu H 5; Pu DC ; Luo JH ; Takebe T2; Ben KL1; kben@21cn.com
	2002
发表期刊	JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
ISSN	1525-4135
卷号	29 期号:2 页码:191-196
合作性质	其它
摘要	The southeastern region of Yunnan province is a key site for drug trafficking and HIV-1 infection spread from the west of Yunnan and Laos to southeastern China. To investigate the prevalence of HIV-1 infection and hepatitis C virus (HCV) coinfection among injection drug users (IDUs) in southeastern Yunnan, three cohorts of 285 addicts, including 242 IDUs and 43 oral drug users, living in the cities of Gejiu and Kaiyuan and the county of Yanshan were studied. HIV-1 and HCV infections were detected by enzyme-linked immunosorbent assay and/or polymerase chain reaction. Data on the age, sex, risk behavior, drug use history, employment, ethnic background, and marriage status were obtained by interview. The overall prevalence of HIV-1 infection was 71.9%. The rate of HCV coinfection among 138 HIV-1-infected IDUs was 99.3%. Most HIV-infected IDUs were 20 to 35 years old (86.7%) and were ethnic Han (75.9%), suggesting that the epidemic in Yunnan is no longer confined to non-Han ethnic minorities, HIV prevalence in female IDUs (81.2%) was significantly higher than in male IDUs (68.2%) (p <.05). The prevalence of HIV infection reached 68.4% after 1 year of injection drug use. Needle/syringe sharing is the major high risk factor for the spread of HIV-1 and HCV infections. Large-scale educational campaigns are urgently needed to reduce the spread of HIV and HCV infection in these regions.
关键词	Hiv Hcv Injection Drug Users Needle/syringe Sharing Prevalence
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收录类别	SCI
语种	英语
文献类型	期刊论文
条目标识符	http://ir.kiz.ac.cn/handle/152453/5247
专题	其他
通讯作者	kben@21cn.com
作者单位	1.Chinese Acad Sci, Kunming Inst Zool, Mol & Cell Immunol Lab, Kunming 650223, Peoples R China 2.Natl Inst Infect Dis, AIDS Res Ctr, Lab Mol Virol & Epidemiol, Tokyo, Japan 3.Honghe Anti Epidem Stn, Gejiu, Yunnan, Peoples R Chi 4.Wenshan Anti Epidem Stn, Wenshan, Yunnan, Peoples R China 5.Chinese Peoples Liberat Army, Hosp 59, Dept Infect Dis, Kaiyuan, Yunnan, Peoples R China
推荐引用方式 GB/T 7714	Zhang CY,Yang RG,Xia XS,et al. High prevalence of HIV-1 and hepatitis C virus coinfection among injection drug users in the southeastern region of Yunnan, China[J]. JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES,2002,29(2):191-196.
APA	Zhang CY.,Yang RG.,Xia XS.,Qin SY.,Dai JP.,...&kben@21cn.com.(2002).High prevalence of HIV-1 and hepatitis C virus coinfection among injection drug users in the southeastern region of Yunnan, China.JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES,29(2),191-196.
MLA	Zhang CY,et al."High prevalence of HIV-1 and hepatitis C virus coinfection among injection drug users in the southeastern region of Yunnan, China".JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES 29.2(2002):191-196.

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