Analysis of the energies of the triple base triplets

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	Analysis of the energies of the triple base triplets
	Liu SQ 1; Yang J 1; Bai CL 2; Liu CQ*1,3; tbrg@public.km.yn.cn
	2002
发表期刊	JOURNAL OF MOLECULAR STRUCTURE-THEOCHEM
ISSN	0166-1280
卷号	578 期号:X 页码:199-207
合作性质	其它
摘要	Sixty-four sets of three-dimensional models of DNA triplex base triplets (TBT) were built up based on codons by homologous modeling method and their energies were minimized. According to sequence of TBT and orientation of the third ODN strand third, the energies of monomers and water-K(+)-TBT ternary complexes of TBT were analyzed. The results showed: (i) The energies of the symmetric parallel monomers are generally lower than those of the symmetric anti-parallel monomers of TBT, but the energies of the symmetric parallel ternary complexes are higher than those of the symmetric anti-parallel ternary complexes of TBT. (ii) No matter TBTs are monomers or ternary complexes, the energies of asymmetric parallel TBTs are generally lower than those of the asymmetric anti-parallel ones. (iii) Although the energies of the parallel TBTs are correlated with those of the anti-parallel ones, the energy differences are significant between them. The results here suggest the sequences of TBTs and the orientations of the third ODN strands are two of the key factors that can influence the formation and stability of TBT.
关键词	Triplet Base Triplets Odn Strand Parallel Orientation Anti-parallel Orientation Energy Analysis
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收录类别	SCI
语种	英语
文献类型	期刊论文
条目标识符	http://ir.kiz.ac.cn/handle/152453/5249
专题	其他细胞与分子进化开放实验室
通讯作者	tbrg@public.km.yn.cn
作者单位	1.Chinese Acad Sci, Kunming Inst Zool, Lab Cellular & Mol Evolut, Kunming 650223, Peoples R China 2.Chinese Acad Sci, Inst Chem, Beijing 100081, Peoples R China 3.Yunnan Univ, Modern Biol Ctr, Kunming 650091, Peoples R China
推荐引用方式 GB/T 7714	Liu SQ,Yang J,Bai CL,et al. Analysis of the energies of the triple base triplets[J]. JOURNAL OF MOLECULAR STRUCTURE-THEOCHEM,2002,578(X):199-207.
APA	Liu SQ,Yang J,Bai CL,Liu CQ*,&tbrg@public.km.yn.cn.(2002).Analysis of the energies of the triple base triplets.JOURNAL OF MOLECULAR STRUCTURE-THEOCHEM,578(X),199-207.
MLA	Liu SQ,et al."Analysis of the energies of the triple base triplets".JOURNAL OF MOLECULAR STRUCTURE-THEOCHEM 578.X(2002):199-207.

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2016110808.pdf（192KB）	期刊论文	出版稿	开放获取	CC BY-NC-SA	请求全文