Detection of potential positive regulatory motifs of transcription in yeast introns by comparative analysis of oligonucleotide frequencies

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	Detection of potential positive regulatory motifs of transcription in yeast introns by comparative analysis of oligonucleotide frequencies
	Zhang J*1,2; Hu J 1; Shi XF 3; Cao H 4; Liu WB 4; zhangjing@ynu.edu.cn
	2003
发表期刊	COMPUTATIONAL BIOLOGY AND CHEMISTRY
ISSN	1476-9271
卷号	27 期号:4-5 页码:497-506
合作性质	其它
摘要	We conducted a comparative statistical analysis of tetra- through hexanucleotide frequencies in two sets of introns of yeast genes. The first set consisted of introns of genes that have transcription rates higher than 30 mRNAs/h while the second set contained introns of genes whose transcription rates were lower than or equal to 10 mRNAs/h. Some oligonucleotides whose occurrence frequencies in the first set of introns are significantly higher than those in the second set of introns were detected. The frequencies of occurrence of most of these detected oligonucleotides are also significantly higher than those in the exons flanking the introns of the first set. Interestingly some of these detected oligonucleotides are the same as well known "signature" sequences of transcriptional regulatory elements. This could imply the existence of potential positive regulatory motifs of transcription in yeast introns.
关键词	Gene Transcription Rate Intron Regulatory Motif Oligonucleotide Frequency Analysis Transcriptional Regulation Yeast
资助者	This work is supported by a grant from Ministry of Education of China for Key Program in Science Researches (00246) and a grant from Yunnan University for Science Research (2002T009xx). ; This work is supported by a grant from Ministry of Education of China for Key Program in Science Researches (00246) and a grant from Yunnan University for Science Research (2002T009xx). ; This work is supported by a grant from Ministry of Education of China for Key Program in Science Researches (00246) and a grant from Yunnan University for Science Research (2002T009xx). ; This work is supported by a grant from Ministry of Education of China for Key Program in Science Researches (00246) and a grant from Yunnan University for Science Research (2002T009xx).
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收录类别	SCI
语种	英语
资助者	This work is supported by a grant from Ministry of Education of China for Key Program in Science Researches (00246) and a grant from Yunnan University for Science Research (2002T009xx). ; This work is supported by a grant from Ministry of Education of China for Key Program in Science Researches (00246) and a grant from Yunnan University for Science Research (2002T009xx). ; This work is supported by a grant from Ministry of Education of China for Key Program in Science Researches (00246) and a grant from Yunnan University for Science Research (2002T009xx). ; This work is supported by a grant from Ministry of Education of China for Key Program in Science Researches (00246) and a grant from Yunnan University for Science Research (2002T009xx).
文献类型	期刊论文
条目标识符	http://ir.kiz.ac.cn/handle/152453/5293
专题	其他细胞与分子进化重点实验室
通讯作者	zhangjing@ynu.edu.cn
作者单位	1.The Center of Applied Statistics, Yunnan University, Kunming 650091, China 2.Department of Computer Science, Yunnan University of Finance and Economics, Kunming 650221, China 3.Key Laboratory of Cellular and Molecular Evolution, Kunming Institute of Zoology, The Chinese Academy of Sciences, Kunming 650223, China 4.The Center of Modern Biology, Yunnan University, Kunming 650091, China
推荐引用方式 GB/T 7714	Zhang J*,Hu J,Shi XF,et al. Detection of potential positive regulatory motifs of transcription in yeast introns by comparative analysis of oligonucleotide frequencies[J]. COMPUTATIONAL BIOLOGY AND CHEMISTRY,2003,27(4-5):497-506.
APA	Zhang J*,Hu J,Shi XF,Cao H,Liu WB,&zhangjing@ynu.edu.cn.(2003).Detection of potential positive regulatory motifs of transcription in yeast introns by comparative analysis of oligonucleotide frequencies.COMPUTATIONAL BIOLOGY AND CHEMISTRY,27(4-5),497-506.
MLA	Zhang J*,et al."Detection of potential positive regulatory motifs of transcription in yeast introns by comparative analysis of oligonucleotide frequencies".COMPUTATIONAL BIOLOGY AND CHEMISTRY 27.4-5(2003):497-506.

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