Influence of physical parameters of sound on the sensory gating effects of N40 in rats

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	Influence of physical parameters of sound on the sensory gating effects of N40 in rats
	Zhou DM 1,2; Ma YY*2; Liu N 2; Chen L 1; He M 3; Miao YD 4; yuanma0716@vip.sina.com
	2008
发表期刊	NEUROSCIENCE LETTERS
ISSN	0304-3940
卷号	432 期号:2 页码:100-104
合作性质	其它
摘要	Sensory gating is the ability of the brain to modulate its sensitivity to incoming stimuli. The N40 component of the auditory evoked potential, evaluated with the paired click paradigm, was used to probe the gating effect in rats. The physical characteristics of the first and second sounds (S I and S2), such as frequency, duration, and intensity, were altered in three experiments in this study. Changes in the physical characteristics of the paired click influenced the gating effect. If the two clicks remained identical, physical characteristics of the stimuli has minimal effects on gating, but if SI was more salient than S2, gating was stronger and the opposite if S I was fainter than S2. The greater the physical difference between S I and S2, the more the gating effect was affected.
关键词	Rat Physical Parameter Frequency Duration Intensity Sensory Gating N40 Auditory Evoked Potential
资助者	This work was supported by the Ministry of Science and Technology of China Grant (2005CB522800), the Knowledge Innovation Projects of the Chinese Academy of Sciences, National Science Foundation of China (NSFC 30470553, 30770700 and 30530270), 973 program (2005CB522803, 2007CB947703), 863 program (O7013810), Chinese-Finnish International Collaboration Project-neuro (30621130076), Pro- gram of CASC (KSCX1-YW-R-33) and National Key Technologies R&D Program. ; This work was supported by the Ministry of Science and Technology of China Grant (2005CB522800), the Knowledge Innovation Projects of the Chinese Academy of Sciences, National Science Foundation of China (NSFC 30470553, 30770700 and 30530270), 973 program (2005CB522803, 2007CB947703), 863 program (O7013810), Chinese-Finnish International Collaboration Project-neuro (30621130076), Pro- gram of CASC (KSCX1-YW-R-33) and National Key Technologies R&D Program. ; This work was supported by the Ministry of Science and Technology of China Grant (2005CB522800), the Knowledge Innovation Projects of the Chinese Academy of Sciences, National Science Foundation of China (NSFC 30470553, 30770700 and 30530270), 973 program (2005CB522803, 2007CB947703), 863 program (O7013810), Chinese-Finnish International Collaboration Project-neuro (30621130076), Pro- gram of CASC (KSCX1-YW-R-33) and National Key Technologies R&D Program. ; This work was supported by the Ministry of Science and Technology of China Grant (2005CB522800), the Knowledge Innovation Projects of the Chinese Academy of Sciences, National Science Foundation of China (NSFC 30470553, 30770700 and 30530270), 973 program (2005CB522803, 2007CB947703), 863 program (O7013810), Chinese-Finnish International Collaboration Project-neuro (30621130076), Pro- gram of CASC (KSCX1-YW-R-33) and National Key Technologies R&D Program.
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收录类别	SCI
语种	英语
资助者	This work was supported by the Ministry of Science and Technology of China Grant (2005CB522800), the Knowledge Innovation Projects of the Chinese Academy of Sciences, National Science Foundation of China (NSFC 30470553, 30770700 and 30530270), 973 program (2005CB522803, 2007CB947703), 863 program (O7013810), Chinese-Finnish International Collaboration Project-neuro (30621130076), Pro- gram of CASC (KSCX1-YW-R-33) and National Key Technologies R&D Program. ; This work was supported by the Ministry of Science and Technology of China Grant (2005CB522800), the Knowledge Innovation Projects of the Chinese Academy of Sciences, National Science Foundation of China (NSFC 30470553, 30770700 and 30530270), 973 program (2005CB522803, 2007CB947703), 863 program (O7013810), Chinese-Finnish International Collaboration Project-neuro (30621130076), Pro- gram of CASC (KSCX1-YW-R-33) and National Key Technologies R&D Program. ; This work was supported by the Ministry of Science and Technology of China Grant (2005CB522800), the Knowledge Innovation Projects of the Chinese Academy of Sciences, National Science Foundation of China (NSFC 30470553, 30770700 and 30530270), 973 program (2005CB522803, 2007CB947703), 863 program (O7013810), Chinese-Finnish International Collaboration Project-neuro (30621130076), Pro- gram of CASC (KSCX1-YW-R-33) and National Key Technologies R&D Program. ; This work was supported by the Ministry of Science and Technology of China Grant (2005CB522800), the Knowledge Innovation Projects of the Chinese Academy of Sciences, National Science Foundation of China (NSFC 30470553, 30770700 and 30530270), 973 program (2005CB522803, 2007CB947703), 863 program (O7013810), Chinese-Finnish International Collaboration Project-neuro (30621130076), Pro- gram of CASC (KSCX1-YW-R-33) and National Key Technologies R&D Program.
文献类型	期刊论文
条目标识符	http://ir.kiz.ac.cn/handle/152453/5477
专题	认知障碍病理学科研部门_动物模型与人类重大疾病机理重点实验室
通讯作者	yuanma0716@vip.sina.com
作者单位	1.State Key Laboratory of Brain and Cognitive Science, Graduate University, Chinese Academy of Sciences and Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, PR China 2.Laboratory of Primate Neuroscience Research and Key Laboratory of Animal Models and Human Disease Mechanisms, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan 650223, PR China 3.Department of Physiology, Kunming Medical College, Kunming, Yunnan, 650031, PR China 4.Department of Science and Technology, People’s Bank of China, Kunming Branch, Kunming, Yunnan, 650000, PR China
推荐引用方式 GB/T 7714	Zhou DM,Ma YY*,Liu N,et al. Influence of physical parameters of sound on the sensory gating effects of N40 in rats[J]. NEUROSCIENCE LETTERS,2008,432(2):100-104.
APA	Zhou DM.,Ma YY*.,Liu N.,Chen L.,He M.,...&yuanma0716@vip.sina.com.(2008).Influence of physical parameters of sound on the sensory gating effects of N40 in rats.NEUROSCIENCE LETTERS,432(2),100-104.
MLA	Zhou DM,et al."Influence of physical parameters of sound on the sensory gating effects of N40 in rats".NEUROSCIENCE LETTERS 432.2(2008):100-104.

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