| Anthraquinones and Lignans from Cassia occidentalis | |
| Li SF1,2; Di YT1; Wang YH1; Tan CJ1; Fang X1; Zhang Y1,2; Zheng YT3; Li L4; He HP1; Li SL*1; Hao XJ*1; lisl@mail.kib.ac.cn; haoxj@mail.kib.ac.cn | |
| 2010 | |
| 发表期刊 | HELVETICA CHIMICA ACTA
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| 卷号 | 93期号:9页码:1795-1802 |
| 合作性质 | 其它 |
| 摘要 | One new anthraquinone glycoside. 6-O-(alpha-L-rhamnopyranosyl (1 -> 6)-beta-D-glucopyranosyl)emodin (1). and two new sesquilignans. seslignanoccidentaliols A (2) and B (3), were isolated from the whole plant of Cassia occidentalis. The structures of the new compounds were established by means of spectroscopic methods, especially 2D-NMR data (H-1.H-1-COSY. HMQC, HMBC. and ROESY). as well as HR-ESI-MS analysis. One previously reported sesquilignan. crythro-guaiacylglycerol-beta-O-4'-(5')-methoxylariciresinol, was revised to be seslignanoccidentaliol A (2). The 6-O-(alpha-L-rhamnopyranosyl(1 -> 6)-beta-D-glucopyranosyl)emodin (1) exhibited moderate anti HIV-1 activity with an EC50 value of 2.90 mu g/ml and a therapeutic-index (TI) value of 260. |
| 资助者 | This work was supported by the National Natural Science Foundation of China (30760306) and the Yunnan Provincial Science Foundation (2006C009Z). ; This work was supported by the National Natural Science Foundation of China (30760306) and the Yunnan Provincial Science Foundation (2006C009Z). ; This work was supported by the National Natural Science Foundation of China (30760306) and the Yunnan Provincial Science Foundation (2006C009Z). ; This work was supported by the National Natural Science Foundation of China (30760306) and the Yunnan Provincial Science Foundation (2006C009Z). |
| 收录类别 | SCI |
| 语种 | 英语 |
| 资助者 | This work was supported by the National Natural Science Foundation of China (30760306) and the Yunnan Provincial Science Foundation (2006C009Z). ; This work was supported by the National Natural Science Foundation of China (30760306) and the Yunnan Provincial Science Foundation (2006C009Z). ; This work was supported by the National Natural Science Foundation of China (30760306) and the Yunnan Provincial Science Foundation (2006C009Z). ; This work was supported by the National Natural Science Foundation of China (30760306) and the Yunnan Provincial Science Foundation (2006C009Z). |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kiz.ac.cn/handle/152453/6373 |
| 专题 | 科研部门_分子免疫药理学(郑永唐) |
| 通讯作者 | lisl@mail.kib.ac.cn; haoxj@mail.kib.ac.cn |
| 作者单位 | 1.State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, P. R. China 2.Graduate School of Chinese Academy of Sciences, Beijing 100049, P. R. China 3.Laboratory of Molecular Immunopharmacology, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, P. R. China 4.Yunnan Pharmacological Laboratories of Natural Products, Kunming Medical College, Kunming 650031, P. R. China |
| 推荐引用方式 GB/T 7714 | Li SF,Di YT,Wang YH,et al. Anthraquinones and Lignans from Cassia occidentalis[J]. HELVETICA CHIMICA ACTA,2010,93(9):1795-1802. |
| APA | Li SF.,Di YT.,Wang YH.,Tan CJ.,Fang X.,...&haoxj@mail.kib.ac.cn.(2010).Anthraquinones and Lignans from Cassia occidentalis.HELVETICA CHIMICA ACTA,93(9),1795-1802. |
| MLA | Li SF,et al."Anthraquinones and Lignans from Cassia occidentalis".HELVETICA CHIMICA ACTA 93.9(2010):1795-1802. |
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