| Chromosome painting shows that skunks (Mephitidae, Carnivora) have highly rearranged karyotypes | |
| Perelman PL*1,2; Graphodatsky AS1; Dragoo JW4; Serdyukova NA1; Stone G6; Cavagna P10; Menotti A6; Nie W5; O'Brien PCM3; Wang J5; Yang F7; pol@bionet.nsc.ru | |
| 2008 | |
| 发表期刊 | CHROMOSOME RESEARCH
 |
| 卷号 | 16期号:8页码:1215–1231 |
| 合作性质 | 其它 |
| 摘要 | The karyotypic relationships of skunks (Mephitidae) with other major clades of carnivores are not yet established. Here, multi-directional chromosome painting was used to reveal the karyological relationships among skunks and between Mephitidae (skunks) and Procyonidae (raccoons). Representative species from three genera of Mephitidae (Mephitis mephitis, 2n = 50; Mephitis macroura, 2n = 50; Conepatus leuconotus, 2n = 46; Spilogale gracilis, 2n = 60) and one species of Procyonidae (Procyon lotor, 2n = 38) were studied. Chromosomal homology was mapped by hybridization of five sets of whole-chromosome paints derived from stone marten (Martes foina, 2n = 38), cat, skunks (M. mephitis; M. macroura) and human. The karyotype of the raccoon is highly conserved and identical to the hypothetical ancestral musteloid karyotype, suggesting that procyonids have a particular importance for establishing the karyological evolution within the caniforms. Ten fission events and five fusion events are necessary to generate the ancestral skunk karyotype from the ancestral carnivore karyotype. Our results show that Mephitidae joins Canidae and Ursidae as the third family of carnivores that are characterized by a high rate of karyotype evolution. Shared derived chromosomal fusion of stone marten chromosomes 6 and 14 phylogenetically links the American hog-nosed skunk and eastern spotted skunk. |
| 关键词 | Evolution Karyotype Procyonidae Raccoon Skunk Stone Marten |
| 资助者 | This study was funded in part by research grants of the Russian Fund for Basic Research, programmes of the Russian Academy of Science: Molecular and Cell Biology, Biosphere Origin and Evolution, Dynamics 1228 P. L. Perelman et al. of Genofunds of Plants, Animals and Human and Integration programme of the Siberian Branch of the Russian Academy of Science (A.S.G.). R.S. was par- tially supported by a grant FMobility of Italian and foreign researchers residing abroad_ from MIUR. The research of G.S. and MER were supported by the Intramural Research Program of the NIH, NCI, CCR, NCI-Frederick. ; This study was funded in part by research grants of the Russian Fund for Basic Research, programmes of the Russian Academy of Science: Molecular and Cell Biology, Biosphere Origin and Evolution, Dynamics 1228 P. L. Perelman et al. of Genofunds of Plants, Animals and Human and Integration programme of the Siberian Branch of the Russian Academy of Science (A.S.G.). R.S. was par- tially supported by a grant FMobility of Italian and foreign researchers residing abroad_ from MIUR. The research of G.S. and MER were supported by the Intramural Research Program of the NIH, NCI, CCR, NCI-Frederick. ; This study was funded in part by research grants of the Russian Fund for Basic Research, programmes of the Russian Academy of Science: Molecular and Cell Biology, Biosphere Origin and Evolution, Dynamics 1228 P. L. Perelman et al. of Genofunds of Plants, Animals and Human and Integration programme of the Siberian Branch of the Russian Academy of Science (A.S.G.). R.S. was par- tially supported by a grant FMobility of Italian and foreign researchers residing abroad_ from MIUR. The research of G.S. and MER were supported by the Intramural Research Program of the NIH, NCI, CCR, NCI-Frederick. ; This study was funded in part by research grants of the Russian Fund for Basic Research, programmes of the Russian Academy of Science: Molecular and Cell Biology, Biosphere Origin and Evolution, Dynamics 1228 P. L. Perelman et al. of Genofunds of Plants, Animals and Human and Integration programme of the Siberian Branch of the Russian Academy of Science (A.S.G.). R.S. was par- tially supported by a grant FMobility of Italian and foreign researchers residing abroad_ from MIUR. The research of G.S. and MER were supported by the Intramural Research Program of the NIH, NCI, CCR, NCI-Frederick. |
| 收录类别 | 其他 |
| 语种 | 英语 |
| 资助者 | This study was funded in part by research grants of the Russian Fund for Basic Research, programmes of the Russian Academy of Science: Molecular and Cell Biology, Biosphere Origin and Evolution, Dynamics 1228 P. L. Perelman et al. of Genofunds of Plants, Animals and Human and Integration programme of the Siberian Branch of the Russian Academy of Science (A.S.G.). R.S. was par- tially supported by a grant FMobility of Italian and foreign researchers residing abroad_ from MIUR. The research of G.S. and MER were supported by the Intramural Research Program of the NIH, NCI, CCR, NCI-Frederick. ; This study was funded in part by research grants of the Russian Fund for Basic Research, programmes of the Russian Academy of Science: Molecular and Cell Biology, Biosphere Origin and Evolution, Dynamics 1228 P. L. Perelman et al. of Genofunds of Plants, Animals and Human and Integration programme of the Siberian Branch of the Russian Academy of Science (A.S.G.). R.S. was par- tially supported by a grant FMobility of Italian and foreign researchers residing abroad_ from MIUR. The research of G.S. and MER were supported by the Intramural Research Program of the NIH, NCI, CCR, NCI-Frederick. ; This study was funded in part by research grants of the Russian Fund for Basic Research, programmes of the Russian Academy of Science: Molecular and Cell Biology, Biosphere Origin and Evolution, Dynamics 1228 P. L. Perelman et al. of Genofunds of Plants, Animals and Human and Integration programme of the Siberian Branch of the Russian Academy of Science (A.S.G.). R.S. was par- tially supported by a grant FMobility of Italian and foreign researchers residing abroad_ from MIUR. The research of G.S. and MER were supported by the Intramural Research Program of the NIH, NCI, CCR, NCI-Frederick. ; This study was funded in part by research grants of the Russian Fund for Basic Research, programmes of the Russian Academy of Science: Molecular and Cell Biology, Biosphere Origin and Evolution, Dynamics 1228 P. L. Perelman et al. of Genofunds of Plants, Animals and Human and Integration programme of the Siberian Branch of the Russian Academy of Science (A.S.G.). R.S. was par- tially supported by a grant FMobility of Italian and foreign researchers residing abroad_ from MIUR. The research of G.S. and MER were supported by the Intramural Research Program of the NIH, NCI, CCR, NCI-Frederick. |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kiz.ac.cn/handle/152453/6379 |
| 专题 | 遗传资源与进化国家重点实验室_保护遗传学(细胞库) |
| 通讯作者 | pol@bionet.nsc.ru |
| 作者单位 | 1.Institute of Cytology and Genetics, SB RAS 630090, Novosibirsk, Russia 2.Laboratory of Genomic Diversity, National Cancer Institute, Frederick, MD 21702 USA 3.Centre for Veterinary Science, Department of Veterinary Medicine, University of Cambridge, Madingley Road, Cambridge CB3 OES, UK 4.Museum of Southwestern Biology, Department of Biology, University of New Mexico, Albuquerque, NM87131, USA 5.Kunming Institute of Zoology, The Chinese Academy of Sciences, Kunming, Yunnan 650223, PR China 6.Comparative Molecular Cytogenetics Core, National Cancer Institute, Frederick, MD 21702, USA 7.Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK 8.Department of Evolutionary Biology, University of Florence, 50122 Florence, Italy 9.Department of Human Genetics, McGill University, Montreal, QC H3G 1A4, Canada 10.Department of Anthropological Sciences, University of Genoa, 16128 Genova, GE, Italy |
| 推荐引用方式 GB/T 7714 | Perelman PL*,Graphodatsky AS,Dragoo JW,et al. Chromosome painting shows that skunks (Mephitidae, Carnivora) have highly rearranged karyotypes[J]. CHROMOSOME RESEARCH,2008,16(8):1215–1231. |
| APA | Perelman PL*.,Graphodatsky AS.,Dragoo JW.,Serdyukova NA.,Stone G.,...&pol@bionet.nsc.ru.(2008).Chromosome painting shows that skunks (Mephitidae, Carnivora) have highly rearranged karyotypes.CHROMOSOME RESEARCH,16(8),1215–1231. |
| MLA | Perelman PL*,et al."Chromosome painting shows that skunks (Mephitidae, Carnivora) have highly rearranged karyotypes".CHROMOSOME RESEARCH 16.8(2008):1215–1231. |
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| 2010111006.pdf（655KB） | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | 请求全文 | |
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