| Chemical Constituents from the Leaves and Stems of Schisandra lancifolia | |
| Xiao WL1; Yang LM2; Zhang HB1,3; Xue YB1,3; Yang GY1,4; Pu JX1; Wang RR2,3; Zheng YT2; Sun HD*1; hdsun@mail.kib.ac.cn | |
| 2010 | |
| 发表期刊 | CHEMICAL & PHARMACEUTICAL BULLETIN
 |
| 卷号 | 58期号:6页码:852-855 |
| 合作性质 | 其它 |
| 摘要 | A new nortriterpenoid, 20-hydroxymicrandilactone D (1) and a novel lignan glycoside, lancilignanside A (2) were isolated from leaves and stems of Schisandra lancifolia, together with three known nortriterpenoids (3—5) and nine known phenolics (6—14). The structures of new compounds 1 and 2 were determined by detailed analysis of their 1D and 2D NMR spectra, and chemical evidences. In addition, compounds 1—2, 6—7, and 9—11 showed anti-human immunodeficiency virus (HIV)-1 activities with 50% effective concentration (EC50) in the range of 3.0—99.0m g/ml. Compound 12 was not bioactive in this assay with EC50 more than 200m g/ml. |
| 关键词 | Nortriterpenoid Lignan Schisandra Lancifolia Anti-human Immunodeficiency Virus-1 Activity |
| 资助者 | This project was supported financially by the NSFC (No. 20802082 and 30830115), the projects from the Chinese Academy of Sciences (“Xibuzhiguang” to W.-L.X and No. KSCX1-YW-R-24), the Yong Academic and Technical Leader Rising Foundation of Yunnan Province (2006PY01-47), and the Major State Basic Research Development Program of China (No. 2009CB522300 and 2009CB940900). ; This project was supported financially by the NSFC (No. 20802082 and 30830115), the projects from the Chinese Academy of Sciences (“Xibuzhiguang” to W.-L.X and No. KSCX1-YW-R-24), the Yong Academic and Technical Leader Rising Foundation of Yunnan Province (2006PY01-47), and the Major State Basic Research Development Program of China (No. 2009CB522300 and 2009CB940900). ; This project was supported financially by the NSFC (No. 20802082 and 30830115), the projects from the Chinese Academy of Sciences (“Xibuzhiguang” to W.-L.X and No. KSCX1-YW-R-24), the Yong Academic and Technical Leader Rising Foundation of Yunnan Province (2006PY01-47), and the Major State Basic Research Development Program of China (No. 2009CB522300 and 2009CB940900). ; This project was supported financially by the NSFC (No. 20802082 and 30830115), the projects from the Chinese Academy of Sciences (“Xibuzhiguang” to W.-L.X and No. KSCX1-YW-R-24), the Yong Academic and Technical Leader Rising Foundation of Yunnan Province (2006PY01-47), and the Major State Basic Research Development Program of China (No. 2009CB522300 and 2009CB940900). |
| 收录类别 | 其他 |
| 语种 | 英语 |
| 资助者 | This project was supported financially by the NSFC (No. 20802082 and 30830115), the projects from the Chinese Academy of Sciences (“Xibuzhiguang” to W.-L.X and No. KSCX1-YW-R-24), the Yong Academic and Technical Leader Rising Foundation of Yunnan Province (2006PY01-47), and the Major State Basic Research Development Program of China (No. 2009CB522300 and 2009CB940900). ; This project was supported financially by the NSFC (No. 20802082 and 30830115), the projects from the Chinese Academy of Sciences (“Xibuzhiguang” to W.-L.X and No. KSCX1-YW-R-24), the Yong Academic and Technical Leader Rising Foundation of Yunnan Province (2006PY01-47), and the Major State Basic Research Development Program of China (No. 2009CB522300 and 2009CB940900). ; This project was supported financially by the NSFC (No. 20802082 and 30830115), the projects from the Chinese Academy of Sciences (“Xibuzhiguang” to W.-L.X and No. KSCX1-YW-R-24), the Yong Academic and Technical Leader Rising Foundation of Yunnan Province (2006PY01-47), and the Major State Basic Research Development Program of China (No. 2009CB522300 and 2009CB940900). ; This project was supported financially by the NSFC (No. 20802082 and 30830115), the projects from the Chinese Academy of Sciences (“Xibuzhiguang” to W.-L.X and No. KSCX1-YW-R-24), the Yong Academic and Technical Leader Rising Foundation of Yunnan Province (2006PY01-47), and the Major State Basic Research Development Program of China (No. 2009CB522300 and 2009CB940900). |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kiz.ac.cn/handle/152453/6431 |
| 专题 | 科研部门_分子免疫药理学（郑永唐） 科研部门_动物模型与人类重大疾病机理重点实验室 |
| 通讯作者 | hdsun@mail.kib.ac.cn |
| 作者单位 | 1.State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences; Kunming 650204, Yunnan, P.R. China 2.Key Laboratory of Animal Models and Human Disease Mechanisms and Laboratory of Molecular Immunopharmacology, Kunming Institute of Zoology, Chinese Academy of Sciences; Kunming 650223, Yunnan, P.R. China 3.Graduate School of the Chinese Academy of Sciences; Beijing 100039, P .R. China 4.Key Laboratory of Tobacco Chemistry of Yunnan Province, Yunnan Academy of Tobacco Science; Kunming 6501064, Yunnan, P.R. China |
| 推荐引用方式 GB/T 7714 | Xiao WL,Yang LM,Zhang HB,et al. Chemical Constituents from the Leaves and Stems of Schisandra lancifolia[J]. CHEMICAL & PHARMACEUTICAL BULLETIN,2010,58(6):852-855. |
| APA | Xiao WL.,Yang LM.,Zhang HB.,Xue YB.,Yang GY.,...&hdsun@mail.kib.ac.cn.(2010).Chemical Constituents from the Leaves and Stems of Schisandra lancifolia.CHEMICAL & PHARMACEUTICAL BULLETIN,58(6),852-855. |
| MLA | Xiao WL,et al."Chemical Constituents from the Leaves and Stems of Schisandra lancifolia".CHEMICAL & PHARMACEUTICAL BULLETIN 58.6(2010):852-855. |
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| 文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
| 2010111058.pdf（343KB） | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | 请求全文 | |
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