| Expression of syncytin in leukemia and lymphoma cells | |
| Sun Y1,2,3; Ouyang DY1,2; Pang W1; Tu YQ1,2; Li YY1,2; Shen XM3; Tam SC4; Yang HY5; Zheng YT*1; zhengyt@mail.kiz.ac.cn | |
| 2010 | |
| 发表期刊 | LEUKEMIA RESEARCH
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| 卷号 | 34期号:9页码:1195–1202 |
| 合作性质 | 其它 |
| 摘要 | Syncytin is a placenta-specific protein and generally believed to play a pivotal role in syncytiotrophoblast morphogenesis. In this study, transcripts of this gene were quantified by real-time RT-PCR and the translated products were measured by an indirect immunofluorescence assay. Results showed that syncytin was found to be expressed in all nine leukemia and lymphoma cell lines studied albeit at different levels and in 43 peripheral blood samples of 57 leukemia or lymphoma patients. Neither the transcripts nor the translated syncytin was detected in blood samples of normal individuals. In conclusion, peripheral blood syncytin may serve as a marker for leukemia and lymphoma. |
| 关键词 | Syncytin Herv-w Ervw1 Leukemia Lymp |
| 资助者 | This work was supported in part by grants from the Western Light of CAS to Y. Sun and the China postdoctoral Science Foun- dation (20090451433) to W. Pang. ; This work was supported in part by grants from the Western Light of CAS to Y. Sun and the China postdoctoral Science Foun- dation (20090451433) to W. Pang. ; This work was supported in part by grants from the Western Light of CAS to Y. Sun and the China postdoctoral Science Foun- dation (20090451433) to W. Pang. ; This work was supported in part by grants from the Western Light of CAS to Y. Sun and the China postdoctoral Science Foun- dation (20090451433) to W. Pang. |
| 收录类别 | SCI |
| 语种 | 英语 |
| 资助者 | This work was supported in part by grants from the Western Light of CAS to Y. Sun and the China postdoctoral Science Foun- dation (20090451433) to W. Pang. ; This work was supported in part by grants from the Western Light of CAS to Y. Sun and the China postdoctoral Science Foun- dation (20090451433) to W. Pang. ; This work was supported in part by grants from the Western Light of CAS to Y. Sun and the China postdoctoral Science Foun- dation (20090451433) to W. Pang. ; This work was supported in part by grants from the Western Light of CAS to Y. Sun and the China postdoctoral Science Foun- dation (20090451433) to W. Pang. |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kiz.ac.cn/handle/152453/6432 |
| 专题 | 科研部门_分子免疫药理学(郑永唐) 科研部门_动物模型与人类重大疾病机理重点实验室 |
| 通讯作者 | zhengyt@mail.kiz.ac.cn |
| 作者单位 | 1.Key Laboratory of Animal Models and Human Disease Mechanisms of Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences, 32 Jiaochang Donglu, Kunming 650223, China 2.Graduate School of the Chinese Academy of Sciences, Beijing, China 3.The First People’s Hospital of Yunnan Province, Kunming, China 4.School of Biomedical Sciences, Chinese University of Hong Kong, Hong Kong, China 5.The Second Affiliated Hospital of Kunming Medical College, Kunming, China |
| 推荐引用方式 GB/T 7714 | Sun Y,Ouyang DY,Pang W,et al. Expression of syncytin in leukemia and lymphoma cells[J]. LEUKEMIA RESEARCH,2010,34(9):1195–1202. |
| APA | Sun Y.,Ouyang DY.,Pang W.,Tu YQ.,Li YY.,...&zhengyt@mail.kiz.ac.cn.(2010).Expression of syncytin in leukemia and lymphoma cells.LEUKEMIA RESEARCH,34(9),1195–1202. |
| MLA | Sun Y,et al."Expression of syncytin in leukemia and lymphoma cells".LEUKEMIA RESEARCH 34.9(2010):1195–1202. |
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